Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition.
(1998)
Journal Article
Hagan, N., Vincent, S., Ingleston, S., Sharples, G., Bennett, R., West, S., & Lloyd, R. (1998). Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition. Journal of Molecular Biology, 281, 17-29
The RuvC protein of Escherichia coli resolves Holliday intermediates in recombination and DNA repair by a dual strand incision mechanism targeted to specific DNA sequences located symmetrically at the crossover. Two classes of amino acid substitution... Read More about Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition..