The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis. (2005)
Journal Article
Sanchez, H., Kidane, D., Reed, P., Curtis, F., Cozar, M., Graumann, P., …Alonso, J. (2005). The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis. Genetics, 171, 873-883

In models of Escherichia coli recombination and DNA repair, the RuvABC complex directs the branch migration and resolution of Holliday junction DNA. To probe the validity of the E. coli paradigm, we examined the impact of mutations in DeltaruvAB and... Read More about The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis..

Functional similarities between phage lambda Orf and Escherichia coli RecFOR in initiation of genetic exchange (2005)
Journal Article
Maxwell, K., Reed, P., Zhang, R., Beasley, S., Walmsley, A., Curtis, F., …Sharples, G. (2005). Functional similarities between phage lambda Orf and Escherichia coli RecFOR in initiation of genetic exchange. Proceedings of the National Academy of Sciences, 102(32), 11260-11265. https://doi.org/10.1073/pnas.0503399102

Genetic recombination in bacteriophage lambda relies on DNA end processing by Exo to expose 3'-tailed strands for annealing and exchange by beta protein. Phage lambda encodes an additional recombinase, Orf, which participates in the early stages of r... Read More about Functional similarities between phage lambda Orf and Escherichia coli RecFOR in initiation of genetic exchange.

Evolution of a phage RuvC endonuclease for resolution of both Holliday and branched DNA junctions (2005)
Journal Article
Curtis, F., Reed, P., & Sharples, G. (2005). Evolution of a phage RuvC endonuclease for resolution of both Holliday and branched DNA junctions. Molecular Microbiology, 55(5), 1332-1345. https://doi.org/10.1111/j.1365-2958.2004.04476.x

Resolution of Holliday junction recombination intermediates in most Gram-negative bacteria is accomplished by the RuvC endonuclease acting in concert with the RuvAB branch migration machinery. Gram-positive species, however, lack RuvC, with the excep... Read More about Evolution of a phage RuvC endonuclease for resolution of both Holliday and branched DNA junctions.