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Multi-scale Approaches to Dynamical Transmission of Protein Allostery (2015)
Presentation / Conference Contribution
Townsend, P., Rodgers, T., Pohl, E., Wilson, M., Cann, M., & McLeish, T. (2015). Multi-scale Approaches to Dynamical Transmission of Protein Allostery. In L. Olivares-Quiroz, O. Guzmán-López, & H. E. Jardón-Valadez (Eds.), Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation (141-152). https://doi.org/10.1007/978-3-319-21687-4_8

We review the idea that allosteric interactions can be transmitted not by structural switching but by the more subtle route of modulation of the amplitude of thermally-activated global dynamical modes in allosteric proteins. The effect is naturally a... Read More about Multi-scale Approaches to Dynamical Transmission of Protein Allostery.

Muon Spectroscopy: an Introduction (2021)
Book
Blundell, S., De Renzi, R., Lancaster, T., & Pratt, F. (Eds.). (2021). Muon Spectroscopy: an Introduction. Oxford University Press

Denoising Diffusion Probabilistic Models on SO(3) for Rotational Alignment (2022)
Presentation / Conference Contribution
Leach, A., Schmon, S. M., Degiacomi, M. T., & Willcocks, C. G. (2022). Denoising Diffusion Probabilistic Models on SO(3) for Rotational Alignment.

Probabilistic diffusion models are capable of modeling complex data distributions on high-dimensional Euclidean spaces for a range applications. However, many real world tasks involve more complex structures such as data distributions defined on mani... Read More about Denoising Diffusion Probabilistic Models on SO(3) for Rotational Alignment.

Adaptive optical methods for in vivo imaging in developing Zebra fish (2012)
Presentation / Conference Contribution
Girkin, J., Taylor, J., Bourgenot, C., Saunter, C., & Love, G. (2012). Adaptive optical methods for in vivo imaging in developing Zebra fish. In 2012 International Symposium on Optomechatronic Technologies (ISOT 2012). https://doi.org/10.1109/isot.2012.6403295

The humble Zebra fish is rapidly establishing itself as the model of choice for a wide range of biological investigations, in particular at the developing embryo stage. Single Plane Illumination Microscopy (SPIM) has already been shown to be a very p... Read More about Adaptive optical methods for in vivo imaging in developing Zebra fish.

Heart synchronization for SPIM microscopy of living zebra fish (2011)
Presentation / Conference Contribution
Taylor, J., Saunter, C., Chaudhry, B., Henderson, D., Love, G., & Girkin, J. (2011). Heart synchronization for SPIM microscopy of living zebra fish. In J. Conchello, C. J. Cogswell, T. Wilson, & T. G. Brown (Eds.), . https://doi.org/10.1117/12.874773

We describe work on producing a selective plane illumination microscope for cardiac imaging in zebra fish embryos. The system has a novel synchronization system for imaging oscillating structures (e.g. the heart) and will have adaptive optics for ima... Read More about Heart synchronization for SPIM microscopy of living zebra fish.

An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets (2013)
Presentation / Conference Contribution
Hargreaves, A. L., Kirby, A. K., Bain, C. D., Love, G. D., Bolognesi, G., Ces, O., …Ward, A. D. (2013). An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets. In K. Dholakia, & G. C. Spalding (Eds.), . https://doi.org/10.1117/12.2027105

We discuss the design, implementation and performance of a novel platform for the production and optical control of ultra-low interfacial tension droplets in the 1-10 micron regime. A custom-designed, integrated microfluidic system allows the product... Read More about An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets.

Shape tracing: An extension of sphere tracing for 3D non-convex collision in protein docking (2020)
Presentation / Conference Contribution
Leach, A., Rudden, L. S., Bond-Taylor, S., Brigham, J. C., Degiacomi, M. T., & Willcocks, C. G. (2020). Shape tracing: An extension of sphere tracing for 3D non-convex collision in protein docking. In 2020 IEEE 20th International Conference on Bioinformatics and Bioengineering (BIBE) (49-52). https://doi.org/10.1109/bibe50027.2020.00016

This paper presents an algorithm, similar to implicit sphere tracing, that ray marches 3D non-convex shapes for efficient collision detection. Instead of finding points on the surface where individual rays strike, an entire shape is marched in unison... Read More about Shape tracing: An extension of sphere tracing for 3D non-convex collision in protein docking.