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Electrostatic control of thickness and stiffness in a designed protein fiber (2008)
Journal Article
Papapostolou, D., Bromley, E., Bano, C., & Woolfson, D. (2008). Electrostatic control of thickness and stiffness in a designed protein fiber. Journal of the American Chemical Society, 130(15), 5124-5130. https://doi.org/10.1021/ja0778444

Attempts to design peptide-based fibers from first principles test our understanding of protein folding and assembly, and potentially provide routes to new biomaterials. Several groups have presented such designs based on a-helical and beta-strand bu... Read More about Electrostatic control of thickness and stiffness in a designed protein fiber.

MagicWand: A single, designed peptide that assembles to stable, ordered alpha-helical fibers (2008)
Journal Article
Gribbon, C., Channon, K., Zhang, W., Banwell, E., Bromley, E., Chaudhuri, J., …Woolfson, D. (2008). MagicWand: A single, designed peptide that assembles to stable, ordered alpha-helical fibers. Biochemistry, 47(39), 10365-10371

We describe a straightforward single-peptide design that self-assembles into extended and thickened nano-to-mesoscale fibers of remarkable stability and order. The basic chassis of the design is the well-understood dimeric a-helical coiled-coil motif... Read More about MagicWand: A single, designed peptide that assembles to stable, ordered alpha-helical fibers.

Synthetic biology through biomolecular design and engineering (2008)
Journal Article
Channon, K., Bromley, E., & Woolfson, D. (2008). Synthetic biology through biomolecular design and engineering. Current Opinion in Structural Biology, 18(4), 491-498

Synthetic biology is a rapidly growing field that has emerged in a global, multidisciplinary effort among biologists, chemists, engineers, physicists, and mathematicians. Broadly, the field has two complementary goals: To improve understanding of bio... Read More about Synthetic biology through biomolecular design and engineering.

Peptide and protein building blocks for synthetic biology: From programming biomolecules to self-organized biomolecular systems (2008)
Journal Article
Bromley, E., Channon, K., Moutevelis, E., & Woolfson, D. (2008). Peptide and protein building blocks for synthetic biology: From programming biomolecules to self-organized biomolecular systems. ACS Chemical Biology, 3(1), 38-50. https://doi.org/10.1021/cb700249v

There are several approaches to creating synthetic-biological systems. Here, we describe a molecular-design approach. First, we lay out a possible synthetic-biology space, which we define with a plot of complexity of components versus divergence from... Read More about Peptide and protein building blocks for synthetic biology: From programming biomolecules to self-organized biomolecular systems.

Electron-Hole Recombination in Uniaxially Aligned Semiconducting Polymers (2008)
Journal Article
Zaumseil, J., Groves, C., Winfield, J., Greenham, N., & Sirringhaus, H. (2008). Electron-Hole Recombination in Uniaxially Aligned Semiconducting Polymers. Advanced Functional Materials, 18(22), 3630-3637. https://doi.org/10.1002/adfm.200800863

A promising, general strategy for improving performance of optoelectronic devices based on conjugated polymer semiconductors is to make better use of the fast intrachain transport along the covalently bonded polymer backbone. Little is known, however... Read More about Electron-Hole Recombination in Uniaxially Aligned Semiconducting Polymers.