Dr Jo Hepworth's Outputs (16)

Flowering time: from physiology, through genetics to mechanism. (2024)
Journal Article
Maple, R., Zhu, P., Hepworth, J., Wang, J.-W., & Dean, C. (2024). Flowering time: from physiology, through genetics to mechanism. Plant Physiology, 195(1), 190–212. https://doi.org/10.1093/plphys/kiae109

Plant species have evolved different requirements for environmental/endogenous cues to induce flowering. Originally, these varying requirements were thought to reflect the action of different molecular mechanisms. Thinking changed when genetic and mo... Read More about Flowering time: from physiology, through genetics to mechanism..

A transcriptomic time-series reveals differing trajectories during pre-floral development in the apex and leaf in winter and spring varieties of Brassica napus (2024)
Journal Article
Jones, D. M., Hepworth, J., Wells, R., Pullen, N., Trick, M., & Morris, R. J. (2024). A transcriptomic time-series reveals differing trajectories during pre-floral development in the apex and leaf in winter and spring varieties of Brassica napus. Scientific Reports, 14(1), Article 3538. https://doi.org/10.1038/s41598-024-53526-x

Oilseed rape (Brassica napus) is an important global oil crop, with spring and winter varieties grown commercially. To understand the transcriptomic differences between these varieties, we collected transcriptomes from apex and leaf tissue from a spr... Read More about A transcriptomic time-series reveals differing trajectories during pre-floral development in the apex and leaf in winter and spring varieties of Brassica napus.

Natural temperature fluctuations promote COOLAIR regulation of FLC (2021)
Journal Article
Zhao, Y., Zhu, P., Hepworth, J., Bloomer, R., Antoniou-Kourounioti, R., Doughty, J., Heckmann, A., Xu, C., Yang, H., & Dean, C. (2021). Natural temperature fluctuations promote COOLAIR regulation of FLC. https://doi.org/10.1101/gad.348362.121

Comparative transcriptomics reveals desynchronisation of gene expression during the floral transition between Arabidopsis and Brassica rapa cultivars (2021)
Journal Article
Calderwood, A., Hepworth, J., Woodhouse, S., Bilham, L., Jones, D., Tudor, E., Ali, M., Dean, C., Wells, R., Irwin, J., & Morris, R. (2021). Comparative transcriptomics reveals desynchronisation of gene expression during the floral transition between Arabidopsis and Brassica rapa cultivars. https://doi.org/10.1017/qpb.2021.6

Total FLC transcript dynamics from divergent paralogue expression explains flowering diversity in Brassica napus (2021)
Journal Article
Calderwood, A., Lloyd, A., Hepworth, J., Tudor, E., Jones, D., Woodhouse, S., Bilham, L., Chinoy, C., Williams, K., Corke, F., Doonan, J., Ostergaard, L., Irwin, J., Wells, R., & Morris, R. (2021). Total FLC transcript dynamics from divergent paralogue expression explains flowering diversity in Brassica napus. New Phytologist, 229(6), 3534-3548. https://doi.org/10.1111/nph.17131

Natural variation in autumn expression is the major adaptive determinant distinguishing arabidopsis flc haplotypes (2020)
Journal Article
Hepworth, J., Antoniou-Kourounioti, R., Berggren, K., Selga, C., Tudor, E., Yates, B., Cox, D., Harris, B., Irwin, J., Howard, M., Säll, T., Holm, S., & Dean, C. (2020). Natural variation in autumn expression is the major adaptive determinant distinguishing arabidopsis flc haplotypes. eLife, 9, 1-30. https://doi.org/10.7554/elife.57671

Unique and contrasting effects of light and temperature cues on plant transcriptional programs (2020)
Journal Article
Jarad, M., Antoniou-Kourounioti, R., Hepworth, J., & Qüesta, J. (2020). Unique and contrasting effects of light and temperature cues on plant transcriptional programs. Transcription, 11(3-4), 134-159. https://doi.org/10.1080/21541264.2020.1820299

Temperature Sensing Is Distributed throughout the Regulatory Network that Controls FLC Epigenetic Silencing in Vernalization (2018)
Journal Article
Antoniou-Kourounioti, R., Hepworth, J., Heckmann, A., Duncan, S., Qüesta, J., Rosa, S., Säll, T., Holm, S., Dean, C., & Howard, M. (2018). Temperature Sensing Is Distributed throughout the Regulatory Network that Controls FLC Epigenetic Silencing in Vernalization. Cell Systems, 7(6), 643-655.e9. https://doi.org/10.1016/j.cels.2018.10.011

Absence of warmth permits epigenetic memory of winter in Arabidopsis (2018)
Journal Article
Hepworth, J., Antoniou-Kourounioti, R., Bloomer, R., Selga, C., Berggren, K., Cox, D., Collier Harris, B., Irwin, J., Holm, S., Säll, T., Howard, M., & Dean, C. (2018). Absence of warmth permits epigenetic memory of winter in Arabidopsis. Nature Communications, 9(1), https://doi.org/10.1038/s41467-018-03065-7

Flowering locus C’s lessons: Conserved chromatin switches underpinning developmental timing and adaptation (2015)
Journal Article
Hepworth, J., & Dean, C. (2015). Flowering locus C’s lessons: Conserved chromatin switches underpinning developmental timing and adaptation. Plant Physiology, 168(4), 1237-1245. https://doi.org/10.1104/pp.15.00496

Regulation of plant lateral-organ growth by modulating cell number and size (2014)
Journal Article
Hepworth, J., & Lenhard, M. (2014). Regulation of plant lateral-organ growth by modulating cell number and size. Current Opinion in Plant Biology, 17(1), 36-42. https://doi.org/10.1016/j.pbi.2013.11.005

Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis (2014)
Journal Article
Zhang, Y., van Dijk, A., Scaffidi, A., Flematti, G., Hofmann, M., Charnikhova, T., Verstappen, F., Hepworth, J., van der Krol, S., Leyser, O., Smith, S., Zwanenburg, B., Al-Babili, S., Ruyter-Spira, C., & Bouwmeester, H. (2014). Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis. Nature Chemical Biology, 10(12), 1028-1033. https://doi.org/10.1038/nchembio.1660

Erratum: Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (2379-2384) DOI: 10.1073/pnas.1317360111) (2014)
Journal Article
Cardoso, C., Zhang, Y., Jamil, M., Hepworth, J., Charnikhova, T., Dimkpa, S., Meharg, C., Wright, M., Liu, J., Meng, X., Wang, Y., Li, J., McCouch, S., Leyser, O., Price, A., Bouwmeester, H., & Carolien, R.-S. (2014). Erratum: Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (2379-2384) DOI: 10.1073/pnas.1317360111). Proceedings of the National Academy of Sciences, 111(17), https://doi.org/10.1073/pnas.1405730111

Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs (2014)
Journal Article
Cardoso, C., Zhang, Y., Jamil, M., Hepworth, J., Charnikhova, T., Dimkpa, S., Meharg, C., Wright, M., Liu, J., Meng, X., Wang, Y., Li, J., McCouch, S., Leyser, O., Price, A., Bouwmeester, H., & Ruyter-Spira, C. (2014). Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs. Proceedings of the National Academy of Sciences, 111(6), 2379-2384. https://doi.org/10.1073/pnas.1317360111

A role for More Axillary Growth1 (MAX1) in evolutionary diversity in strigolactone signaling upstream of MAX2 (2013)
Journal Article
Challis, R., Hepworth, J., Mouchel, C., Waites, R., & Leyser, O. (2013). A role for More Axillary Growth1 (MAX1) in evolutionary diversity in strigolactone signaling upstream of MAX2. Plant Physiology, 161(4), 1885-1902. https://doi.org/10.1104/pp.112.211383

Strigolactones enhance competition between shoot branches by dampening auxin transport (2010)
Journal Article
Crawford, S., Shinohara, N., Sieberer, T., Williamson, L., George, G., Hepworth, J., Müller, D., Domagalska, M., & Leyser, O. (2010). Strigolactones enhance competition between shoot branches by dampening auxin transport. Development, 137(17), 2905-2913. https://doi.org/10.1242/dev.051987