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Dr Juan Aguilar Malavia's Outputs (4)

Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers (2018)
Journal Article
Gimenez, D., Aguilar, J., Bromley, E., & Cobb, S. (2018). Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers. Angewandte Chemie International Edition, 57(33), 10549-10553. https://doi.org/10.1002/anie.201804488

Stability towards protease degradation combined with modular synthesis has made peptoids of considerable interest in the fields of chemical biology, medicine, and biomaterials. Given their tertiary amide backbone, peptoids lack the capacity to hydrog... Read More about Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers.

Separating the coherence transfer from chemical shift evolution in high-resolution pure shift COSY NMR (2018)
Journal Article
Aguilar, J. A., Belda, R., Gaunt, B. R., Kenwright, A. M., & Kuprov, I. (2018). Separating the coherence transfer from chemical shift evolution in high-resolution pure shift COSY NMR. Magnetic Resonance in Chemistry, 56(10), 969-975. https://doi.org/10.1002/mrc.4727

Recent developments in data sampling and processing techniques have made it possible to acquire 2‐dimensional NMR spectra of small molecules at digital resolutions in both dimensions approaching the intrinsic limitations of the equipment and sample o... Read More about Separating the coherence transfer from chemical shift evolution in high-resolution pure shift COSY NMR.

On the antibacterial activity of azacarboxylate ligands: lowered metal ion affinities for bis-amide derivatives of EDTA do not mean reduced activity (2018)
Journal Article
Mulla, R. S., Beecroft, M. S., Pal, R., Aguilar, J., Pitarch-Jarque, J., García‐España, E., Lurie-Luke, E., Sharples, G., & Williams, J. (2018). On the antibacterial activity of azacarboxylate ligands: lowered metal ion affinities for bis-amide derivatives of EDTA do not mean reduced activity. Chemistry - A European Journal, 24(28), 7137-7148. https://doi.org/10.1002/chem.201800026

EDTA is widely used as an inhibitor of bacterial growth, affecting the uptake and control of metal ions by microorganisms. We describe the synthesis and characterisation of two symmetrical bis‐amide derivatives of EDTA, featuring glycyl or pyridyl su... Read More about On the antibacterial activity of azacarboxylate ligands: lowered metal ion affinities for bis-amide derivatives of EDTA do not mean reduced activity.

Compressed NMR: Combining compressive sampling and pure shift NMR techniques (2018)
Journal Article
Aguilar, J. A., & Kenwright, A. M. (2018). Compressed NMR: Combining compressive sampling and pure shift NMR techniques. Magnetic Resonance in Chemistry, 56(10), 983-992. https://doi.org/10.1002/mrc.4705

Historically, the resolution of multidimensional nuclear magnetic resonance (NMR) has been orders of magnitude lower than the intrinsic resolution that NMR spectrometers are capable of producing. The slowness of Nyquist sampling as well as the existe... Read More about Compressed NMR: Combining compressive sampling and pure shift NMR techniques.