Dr Amy Hall's Outputs (8)

The interplay between hydrogen bonds and stacking/T-type interactions in molecular cocrystals (2024)
Journal Article
Cruz-Cabeza, A., Spackman, P., & Hall, A. (2024). The interplay between hydrogen bonds and stacking/T-type interactions in molecular cocrystals. Communications Chemistry, 7(1), Article 284. https://doi.org/10.1038/s42004-024-01380-3

Supramolecular synthon and hydrogen bond pairing approaches have influenced the understanding of cocrystal formation for decades, but are hydrogen bonds really the dominant interaction in cocrystals? To investigate this, an extensive analysis of 1:1... Read More about The interplay between hydrogen bonds and stacking/T-type interactions in molecular cocrystals.

Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work (2024)
Journal Article
Cramman, H., Arenas, B., Awais, R., Balaban, C., Cropper, C., Dennis, F., Finch, K., Gray, H., Hall, A., Kitchen, G., Norman, K., O’Driscoll, L., Petts, P., Petri, S., Robson, J., Rosenburgh, A., Shields, L., Swift, G. P., & Vaughan, H. (2024). Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work. Enhancing Teaching and Learning in Higher Education, 2, 39-69. https://doi.org/10.62512/etlhe.14

This paper presents the findings from a detailed study investigating UK undergraduate students’ experience of practical science in their post-16 studies during the COVID-19 pandemic. It also examines their perceived confidence and preparedness in rel... Read More about Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work.

What Has Carbamazepine Taught Crystal Engineers? (2024)
Journal Article
Hall, A. V., Cruz-Cabeza, A. J., & Steed, J. W. (2024). What Has Carbamazepine Taught Crystal Engineers?. Crystal Growth and Design, 24(17), 7342-7360. https://doi.org/10.1021/acs.cgd.4c00555

The antiepilepsy drug carbamazepine is one of the most studied pharmaceuticals in the world. The rich story of its solid forms, cocrystals, and formulation is a microcosm of the topical world of pharmaceutical materials. Understanding carbamazepine h... Read More about What Has Carbamazepine Taught Crystal Engineers?.

Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine (2022)
Journal Article
Hall, A. V., Gostick, I. E., Yufit, D. S., Marchant, G. Y., Kirubakaran, P., Madu, S. J., Li, M., Steel, P. G., & Steed, J. W. (2022). Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine. Crystal Growth and Design, 22(10), 6262-6266. https://doi.org/10.1021/acs.cgd.2c00843

Miltefosine is a repurposed anticancer drug and currently the only orally administered drug approved to treat the neglected tropical disease leishmaniasis. Miltefosine is hygroscopic and must be stored at subzero temperatures. In this work, we report... Read More about Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine.

Anisotropic thermal expansion effects in layered n-Alkyl carboxylic acid – bipyridyl cocrystals (2021)
Journal Article
Hall, A. V., Yufit, D. S., Zhang, Y., Musa, O. M., & Steed, J. W. (2021). Anisotropic thermal expansion effects in layered n-Alkyl carboxylic acid – bipyridyl cocrystals. Supramolecular Chemistry, 33(10), https://doi.org/10.1080/10610278.2022.2117623

Cocrystallisation of butanoic acid (BA), pentanoic acid (PA), and eicosanoic acid (EA) with 4,4’-azopyridine (azp) and trans-1,2-bis(4-pyridyl)ethylene (bpe) results in 2:1 lamellar cocrystals. All cocrystals display the OH···Npyridyl seven-membered... Read More about Anisotropic thermal expansion effects in layered n-Alkyl carboxylic acid – bipyridyl cocrystals.

Properties and Applications of Stimuli-Responsive Diacetylenes (2021)
Journal Article
Hall, A. V., Musa, O. M., & Steed, J. W. (2021). Properties and Applications of Stimuli-Responsive Diacetylenes. Crystal Growth and Design, 21(6), 3614-3638. https://doi.org/10.1021/acs.cgd.1c00300

The topochemical reactivity of diacetylene monomers has long been established and involves the 1,4-addition polymerization reaction. This reaction is governed by well-defined parameters that allow the synthesis of diacetylene polymers. Polydiacetylen... Read More about Properties and Applications of Stimuli-Responsive Diacetylenes.

Alkali Metal Salts of 10,12-Pentacosadiynoic Acid and Their Dosimetry Applications (2021)
Journal Article
Hall, A. V., Musa, O. M., Hood, D. K., Apperley, D. C., Yufit, D. S., & Steed, J. W. (2021). Alkali Metal Salts of 10,12-Pentacosadiynoic Acid and Their Dosimetry Applications. Crystal Growth and Design, 21(4), 2416-2422. https://doi.org/10.1021/acs.cgd.1c00031

Wide-dose-range 2D radiochromic films for radiotherapy, such as GAFchromic EBT, are based on the lithium salt of 10,12-pentacosadiynoic acid (Li-PCDA) as the photosensitive component. We show that there are two solid forms of Li-PCDA—a monohydrated f... Read More about Alkali Metal Salts of 10,12-Pentacosadiynoic Acid and Their Dosimetry Applications.

The crystal engineering of radiation-sensitive diacetylene cocrystals and salts (2020)
Journal Article
Hall, A. V., Yufit, D. S., Apperley, D. C., Senak, L., Musa, O. M., Hood, D. K., & Steed, J. W. (2020). The crystal engineering of radiation-sensitive diacetylene cocrystals and salts. Chemical Science, 11(30), 8025-8035. https://doi.org/10.1039/d0sc02540b

In this work we develop photoreactive cocrystals/salts of a commercially-important diacetylene, 10,12- pentacosadiynoic acid (PCDA, 1) and report the first X-ray crystal structures of PCDA based systems. The topochemical reactivity of the system is m... Read More about The crystal engineering of radiation-sensitive diacetylene cocrystals and salts.