Dr Prashant Kumar's Outputs (2)

Fast tyrosinase detection in early stage melanoma with nanomolar sensitivity using a naphthalimide-based fluorescent read-out probe (2020)
Journal Article
Kumar, P., Biswas, S., & Koner, A. L. (2020). Fast tyrosinase detection in early stage melanoma with nanomolar sensitivity using a naphthalimide-based fluorescent read-out probe. New Journal of Chemistry, 44(26), 10771-10775. https://doi.org/10.1039/d0nj02256j

Naphthalimide-based red-emitting fluorescent read-out probes are developed for expeditious and sensitive detection of tyrosinase activity in live-cells. The probes show excellent photostability, pH-tolerance, specificity among several bio-analytes, n... Read More about Fast tyrosinase detection in early stage melanoma with nanomolar sensitivity using a naphthalimide-based fluorescent read-out probe.

Deciphering interior polarity of lysosome in live cancer and normal cells using spectral scanning microscopy (2020)
Journal Article
Pal, K., Kumar, P., & Koner, A. L. (2020). Deciphering interior polarity of lysosome in live cancer and normal cells using spectral scanning microscopy. Journal of Photochemistry and Photobiology B: Biology, 206, Article 111848. https://doi.org/10.1016/j.jphotobiol.2020.111848

A lysosome specific, pH tolerant, and polarity-sensitive fluorescent probe (LyPol) is designed and synthesized for the determination of lysosomal polarity in live cells. LyPol possesses an intramolecular charge transfer (ICT) properties with high qua... Read More about Deciphering interior polarity of lysosome in live cancer and normal cells using spectral scanning microscopy.