Dr Prashant Kumar prashant.kumar@durham.ac.uk
Post Doctoral Research Associate
Fast tyrosinase detection in early stage melanoma with nanomolar sensitivity using a naphthalimide-based fluorescent read-out probe
Kumar, Prashant; Biswas, Suprakash; Koner, Apurba Lal
Authors
Suprakash Biswas
Apurba Lal Koner
Abstract
Naphthalimide-based red-emitting fluorescent read-out probes are developed for expeditious and sensitive detection of tyrosinase activity in live-cells. The probes show excellent photostability, pH-tolerance, specificity among several bio-analytes, non-toxicity and extremely fast kinetics for tyrosinase detection with nanomolar sensitivity. The probe is also highly suitable for early melanoma detection.
Citation
Kumar, P., Biswas, S., & Koner, A. L. (2020). Fast tyrosinase detection in early stage melanoma with nanomolar sensitivity using a naphthalimide-based fluorescent read-out probe. New Journal of Chemistry, 44(26), 10771-10775. https://doi.org/10.1039/d0nj02256j
| Journal Article Type | Article |
|---|---|
| Acceptance Date | May 31, 2020 |
| Online Publication Date | Jun 1, 2020 |
| Publication Date | Jul 14, 2020 |
| Deposit Date | Jul 10, 2024 |
| Journal | New Journal of Chemistry |
| Print ISSN | 1144-0546 |
| Electronic ISSN | 1369-9261 |
| Publisher | Royal Society of Chemistry |
| Peer Reviewed | Peer Reviewed |
| Volume | 44 |
| Issue | 26 |
| Pages | 10771-10775 |
| DOI | https://doi.org/10.1039/d0nj02256j |
| Public URL | https://durham-repository.worktribe.com/output/2523466 |
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