Evaluation of the Leishmania inositol phosphorylceramide synthase as a drug target using a chemical and genetic approach
(2024)
Journal Article
Denny, P. (online). Evaluation of the Leishmania inositol phosphorylceramide synthase as a drug target using a chemical and genetic approach. ACS Infectious Diseases,
The lack of effective vaccines and the development of resistance to the current treatments highlights the urgent need for new antileishmanials. Sphingolipid metabolism has been proposed as a promising source of Leishmania-specific targets as these li... Read More about Evaluation of the Leishmania inositol phosphorylceramide synthase as a drug target using a chemical and genetic approach.