David Parker's Outputs (5)

Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates (2004)
Journal Article
Fulton, D., O'Halloran, M., Parker, D., Senanayake, K., Botta, M., & Aime, S. (2005). Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates. Chemical Communications, 2005(4), 474-476. https://doi.org/10.1039/B413536A

Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA (2004)
Journal Article
Thompson, N., Parker, D., Schmitt-Willich, H., Sulzle, D., Muller, G., & Riehl, J. (2004). NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA. Dalton Transactions, 1892-1895. https://doi.org/10.1039/B403863K

The solution structure of the diastereoisomers of (S)-Eu-EOB-DTPA has been analysed by H-1 NMR, CD and CPL spectroscopy. Two major species exist which possess very similar 1H NMR paramagnetic shifts and emission spectra, consistent with a 9-coordinat... Read More about NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA.

Design, synthesis and evaluation of ratiometric probes for hydrogencarbonate based on europium emission (2004)
Journal Article
Bretonniere, Y., Cann, M., Parker, D., & Slater, R. (2004). Design, synthesis and evaluation of ratiometric probes for hydrogencarbonate based on europium emission. Organic and Biomolecular Chemistry, 2(11), 1624-1632. https://doi.org/10.1039/b400734b

A series of cationic, zwitterionic and anionic macrocyclic europium complexes has been prepared incorporating a N or C- linked acridone chromophore that allows sensitisation of Eu emission following excitation at 390-410nm. Each of these complexes se... Read More about Design, synthesis and evaluation of ratiometric probes for hydrogencarbonate based on europium emission.

Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex (2004)
Journal Article
Congreve, A., Parker, D., Gianolio, E., & Botta, M. (2004). Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex. Dalton Transactions, 2004(9), 1441-1445. https://doi.org/10.1039/B402230K

Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL(1)], bearing an N-linked CH2CH2NHCO-pyridyl moiety,... Read More about Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex.

Excitement in f block : structure, dynamics and function of nine-coordinate chiral lanthanide complexes in aqueous media (2004)
Journal Article
Parker, D. (2004). Excitement in f block : structure, dynamics and function of nine-coordinate chiral lanthanide complexes in aqueous media. Chemical Society Reviews, 33(3), 156-165. https://doi.org/10.1039/b311001j

Lanthanide complexation chemistry has been studied intensively over the past 15 years and progress has been stimulated by the advent of well-defined, kinetically robust systems tailored to applications as bioactive probes for magnetic resonance and l... Read More about Excitement in f block : structure, dynamics and function of nine-coordinate chiral lanthanide complexes in aqueous media.