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Dr Piotr Stepien's Outputs (2)

A DNA Origami Bubble Blower for Liposome Production (2024)
Journal Article
Wilkens, G. D., Stępień, P., Sakai, Y., Islam, M. S., & Heddle, J. G. (2024). A DNA Origami Bubble Blower for Liposome Production. ACS Omega, 9(43), 43609–43615. https://doi.org/10.1021/acsomega.4c05297

While liposomes are commonly produced on the industrial scale with diameters in the hundreds of nanometers to micrometer size range, the variation from the mean diameter can be significant. In nature, functional liposome-like systems can be as small... Read More about A DNA Origami Bubble Blower for Liposome Production.

CRAFTing Delivery of Membrane Proteins into Protocells using Nanodiscs (2023)
Journal Article
Stępień, P., Świątek, S., Robles, M. Y. Y., Markiewicz-Mizera, J., Balakrishnan, D., Inaba-Inoue, S., …Heddle, J. G. (2023). CRAFTing Delivery of Membrane Proteins into Protocells using Nanodiscs. ACS Applied Materials and Interfaces, https://doi.org/10.1021/acsami.3c11894

For the successfulgenerativeengineeringof functionalartificialcells,a convenientandcontrollablemeansof deliveringmembraneproteinsinto membranelipidbilayersis necessary.Herewereporta deliverysystemthatachievesthis by employingmembraneprotein-carryingn... Read More about CRAFTing Delivery of Membrane Proteins into Protocells using Nanodiscs.