Very bright europium complexes that stain cellular mitochondria.

Walton, J.W.; Bourdoll, A.; Butler, S.J.; Soulie, M.; Delbianco, M.; McMahon, B.K.; Pal, R.; Puschmann, H.; Zwier, J.M.; Lamarque, L.; Maury, O.; Andraud, C.; Parker, D.

doi:10.1039/c2cc35247h

All Outputs (6)

Responsive MR-imaging probes for N-methyl-D-aspartate receptors and direct visualisation of the cell-surface receptors by optical microscopy (2013)
Journal Article
Sim, N., Gottschalk, S., Pal, R., Engelmann, J., Parker, D., & Mishra, A. (2013). Responsive MR-imaging probes for N-methyl-D-aspartate receptors and direct visualisation of the cell-surface receptors by optical microscopy. Chemical Science, 4(8), 3148-3153. https://doi.org/10.1039/c3sc50903f

Bright Mono-aqua Europium Complexes Based on Triazacyclononane That Bind Anions Reversibly and Permeate Cells Efficiently (2013)
Journal Article
Butler, S. J., McMahon, B. K., Pal, R., Parker, D., & Walton, J. W. (2013). Bright Mono-aqua Europium Complexes Based on Triazacyclononane That Bind Anions Reversibly and Permeate Cells Efficiently. Chemistry - A European Journal, 19(29), 9511-9517. https://doi.org/10.1002/chem.201301273

Microscopic visualisation of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probes (2013)
Other
Mishra, A., Mishra, R., Gottschalk, S., Pal, R., Sim, N., Engelmann, J., …Parker, D. (2014). Microscopic visualisation of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probes

A series of bimodal metabotropic glutamate-receptor targeted MRI contrast agents has been developed and evaluated, based on established competitive metabotropic Glu receptor subtype 5 (mGluR5) antagonists. In order to directly visualize mGluR5 bindin... Read More about Microscopic visualisation of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probes.

Complete stereocontrol in the synthesis of macrocyclic lanthanide complexes: direct formation of enantiopure systems for circularly polarised luminescence applications. (2013)
Journal Article
Evans, N. H., Carr, R., Delbianco, M., Pal, R., Yufit, D. S., & Parker, D. (2013). Complete stereocontrol in the synthesis of macrocyclic lanthanide complexes: direct formation of enantiopure systems for circularly polarised luminescence applications. Dalton Transactions, 42(44), 15610-6. https://doi.org/10.1039/c3dt52425f

Mono-C-substitution of the 1,4,7-triazacyclononane ring induces formation of single enantiomers of Eu(III) complexes with nonadentate N6O3 ligands. The absolute configuration of each complex is determined by the stereogenicity of the C-substituent, r... Read More about Complete stereocontrol in the synthesis of macrocyclic lanthanide complexes: direct formation of enantiopure systems for circularly polarised luminescence applications..

A bright and responsive europium probe for determination of pH change within the endoplasmic reticulum of living cells. (2013)
Journal Article
McMahon, B. K., Pal, R., & Parker, D. (2013). A bright and responsive europium probe for determination of pH change within the endoplasmic reticulum of living cells. Chemical Communications, 49(47), 5363-5365. https://doi.org/10.1039/c3cc42308e

A ratiometric EuIII complex has been developed that localises selectively within the endoplasmic reticulum of living cells. Careful calibration, using a time-gated spectral imaging microscope, allows the intensity ratio of emission bands and the vari... Read More about A bright and responsive europium probe for determination of pH change within the endoplasmic reticulum of living cells..

Very bright europium complexes that stain cellular mitochondria. (2013)
Journal Article
Walton, J., Bourdoll, A., Butler, S., Soulie, M., Delbianco, M., McMahon, B., …Parker, D. (2013). Very bright europium complexes that stain cellular mitochondria. Chemical Communications, 49(16), 1600-1602. https://doi.org/10.1039/c2cc35247h

The synthesis, structure and photophysical properties of a series of highly emissive europium complexes is reported. Certain complexes enter mammalian cells by macropinocytosis and stain the mitochondria selectively, allowing observation of the Eu em... Read More about Very bright europium complexes that stain cellular mitochondria..