All Outputs (3)

Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues (2015)
Journal Article
Shenker, N., Flower, K., Wilhelm-Benartzi, C., Dai, W., Bell, E., Gore, E., …Flanagan, J. (2015). Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues. BMC Cancer, 15(1), Article 337. https://doi.org/10.1186/s12885-015-1335-5

Background DNA methylation variability regions (MVRs) across the oestrogen receptor alpha (ESR1) gene have been identified in peripheral blood cells from breast cancer patients and healthy individuals. In contrast to promoter methylation, gene body m... Read More about Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues.

Review of processing and analysis methods for DNA methylation array data (2013)
Journal Article
Wilhelm-Benartzi, C., Koestler, D., Karagas, M., Flanagan, J., Christensen, B., Kelsey, K., …Brown, R. (2013). Review of processing and analysis methods for DNA methylation array data. British Journal of Cancer, 109(6), 1394-1402. https://doi.org/10.1038/bjc.2013.496

The promise of epigenome-wide association studies and cancer-specific somatic DNA methylation changes in improving our understanding of cancer, coupled with the decreasing cost and increasing coverage of DNA methylation microarrays, has brought about... Read More about Review of processing and analysis methods for DNA methylation array data.

DNA Methylation Profiling using Infinium Methylation Assay (2013)
Journal Article
Zeller, C., Masrour, N., Patel, N., Dai, W., Wilhelm-Benartzi, C., & Brown, R. (2013). DNA Methylation Profiling using Infinium Methylation Assay. Bio-protocol, 3(10), Article e777. https://doi.org/10.21769/bioprotoc.777

The Infinium Human Methylation 450 BeadChip technology allows the rapid quantitative DNA methylation analysis of more than 485,000 CpG dinucleotides located across the genome. The method utilizes sodium bisulfite treatment of genomic DNA to convert u... Read More about DNA Methylation Profiling using Infinium Methylation Assay.