Andrea Simkus andrea.simkus@durham.ac.uk
PGR Student Doctor of Philosophy
Andrea Simkus andrea.simkus@durham.ac.uk
PGR Student Doctor of Philosophy
Dr Tahani Coolen-Maturi tahani.maturi@durham.ac.uk
Professor
Professor Frank Coolen frank.coolen@durham.ac.uk
Professor
Claus Bendtsen
Reproducibility is a widely discussed topic, yet many experimental results cannot be confirmed due to factors such as publication bias, poor documentation, and inappropriate statistical methods. A lack of standard definitions for reproducibility and related terms further complicates the matter. This paper reviews the literature on reproducibility, clarifies key terminology by defining five types of reproducibility, and addresses variations in published definitions by considering changes in datasets, labs, and experimental conditions. We explore the causes of low reproducibility in scientific studies and discuss statistical perspectives on quantifying and improving reproducibility. In particular, we propose framing statistical reproducibility as a predictive problem, providing a framework to evaluate and address reproducibility challenges.
Simkus, A., Coolen-Maturi, T., Coolen, F. P., & Bendtsen, C. (2025). Statistical Perspectives on Reproducibility: Definitions and Challenges. Journal of statistical theory and practice, 19(3), Article 40. https://doi.org/10.1007/s42519-025-00459-x
Journal Article Type | Article |
---|---|
Acceptance Date | May 14, 2025 |
Online Publication Date | May 27, 2025 |
Publication Date | Sep 1, 2025 |
Deposit Date | May 15, 2025 |
Publicly Available Date | Jun 2, 2025 |
Journal | Journal of Statistical Theory and Practice |
Electronic ISSN | 1559-8616 |
Publisher | Springer |
Peer Reviewed | Peer Reviewed |
Volume | 19 |
Issue | 3 |
Article Number | 40 |
DOI | https://doi.org/10.1007/s42519-025-00459-x |
Keywords | Preclinical research, Replicability, Nonparametric predictive inference, Reproducibility, Statistical reproducibility |
Public URL | https://durham-repository.worktribe.com/output/3948469 |
Published Journal Article
(857 Kb)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/
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