Professor Rus Hoelzel a.r.hoelzel@durham.ac.uk
Professor
Professor Rus Hoelzel a.r.hoelzel@durham.ac.uk
Professor
Dr Georgios Gkafas georgios.a.gkafas@durham.ac.uk
Academic Visitor
Hui Kang
Fatih Sarigol
Burney Le Boeuf
Daniel P Costa
Roxanne S Beltran
Joanne Reiter
Patrick W Robinson
Nancy McInerney
Inge Seim
Shuai Sun
Guangyi Fan
Songhai Li
Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal (Mirounga angustirostris), recover rapidly even when the surviving population was small. The northern elephant seal was hunted extensively and taken by collectors between the early 1800s and 1892, suffering an extreme population bottleneck as a consequence. Recovery was rapid and now there are over 200,000 individuals. We sequenced 260 modern and 8 historical northern elephant seal nuclear genomes to assess the impact of the population bottleneck on individual northern elephant seals and to better understand their recovery. Here we show that inbreeding, an increase in the frequency of alleles compromised by lost function, and allele frequency distortion, reduced the fitness of breeding males and females, as well as the performance of adult females on foraging migrations. We provide a detailed investigation of the impact of a severe bottleneck on fitness at the genomic level and report on the role of specific gene systems. [Abstract copyright: © 2024. The Author(s).]
Hoelzel, A. R., Gkafas, G. A., Kang, H., Sarigol, F., Le Boeuf, B., Costa, D. P., …Li, S. (2024). Genomics of post-bottleneck recovery in the northern elephant seal. Nature Ecology and Evolution, 8, 686-694. https://doi.org/10.1038/s41559-024-02337-4
Journal Article Type | Article |
---|---|
Acceptance Date | Jan 19, 2024 |
Online Publication Date | Feb 21, 2024 |
Publication Date | 2024-04 |
Deposit Date | Mar 21, 2024 |
Publicly Available Date | Mar 21, 2024 |
Journal | Nature ecology & evolution |
Publisher | Nature Research |
Peer Reviewed | Peer Reviewed |
Volume | 8 |
Pages | 686-694 |
DOI | https://doi.org/10.1038/s41559-024-02337-4 |
Public URL | https://durham-repository.worktribe.com/output/2313817 |
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