D.E. McMillan
Interference of homonuclear decoupling and exchange in the solid-state NMR of perfluorocyclohexane
McMillan, D.E.; Hazendonk, P.; Hodgkinson, P.
Abstract
We observe an interference between RF irradiation used for homonuclear decoupling of F-19 and conformational exchange in the C-13 spectrum of perfluorocyclohexane. We show that these effects can be readily reproduced in simulation, and characterise their dependence on the various NMR and experimental parameters. Their application to observing exchange rates on the kHz timescale is evaluated with respect to T-1p measurements and the connections between the two approaches established. The implications for experiments that use homonuclear decoupling of H-1 to resolve (1)J(CH) couplings in the solid-state are also evaluated in detail. (C) 2003 Elsevier Science (USA). All rights reserved.
Citation
McMillan, D., Hazendonk, P., & Hodgkinson, P. (2003). Interference of homonuclear decoupling and exchange in the solid-state NMR of perfluorocyclohexane. Journal of Magnetic Resonance, 161(2), 234-241
Journal Article Type | Article |
---|---|
Publication Date | 2003-04 |
Journal | Journal of Magnetic Resonance |
Print ISSN | 1090-7807 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 161 |
Issue | 2 |
Pages | 234-241 |
Public URL | https://durham-repository.worktribe.com/output/1569570 |
You might also like
The essential synergy of MD simulation and NMR in understanding amorphous drug forms
(2024)
Journal Article
Revisiting the Van Vleck second moment for characterizing molecular motion in organic solids
(2023)
Journal Article