Synthesis and characterisation of highly emissive and kinetically stable lanthanide complexes suitable for usage 'in cellulo'
Poole, R.A.; Bobba, G.; Cann, M.J.; Frias, J.C.; Parker, D.; Peacock, R.D.
Professor Martin Cann email@example.com
Professor David Parker firstname.lastname@example.org
The synthesis and photophysical characterisation are reported of a series of cationic, neutral and anionic europium and terbium complexes based on structurally related, nonadentate ligands based on the cyclen macrocycle. Each complex incorporates a tetraazatriphenylene moiety and overall absolute emission quantum yields are in the range 15 - 40% in aerated aqueous media. Dynamic quenching of the lanthanide excited state occurs with electron-rich donors, e. g. iodide, ascorbate and urate, and a mechanistic interpretation is put forward involving an electron transfer process. The cationic lanthanide complexes are taken up by N1H/ 3T3 cells and tend to localise inside the cell nucleus.
Poole, R., Bobba, G., Cann, M., Frias, J., Parker, D., & Peacock, R. (2005). Synthesis and characterisation of highly emissive and kinetically stable lanthanide complexes suitable for usage 'in cellulo'. Organic and Biomolecular Chemistry, 3(6), 1013-1024. https://doi.org/10.1039/b418964g
|Journal Article Type||Article|
|Deposit Date||Apr 20, 2007|
|Journal||Organic and Biomolecular Chemistry|
|Publisher||Royal Society of Chemistry|
|Peer Reviewed||Peer Reviewed|