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DNA duplex cage structures with icosahedral symmetry

Grayson, N.E.; Taormina, A.; Twarock, R.

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N.E. Grayson

R. Twarock


A construction method for duplex cage structures with icosahedral symmetry made out of single-stranded DNA molecules is presented and applied to an icosidodecahedral cage. It is shown via a mixture of analytic and computer techniques that there exist realisations of this graph in terms of two circular DNA molecules. These blueprints for the organisation of a cage structure with a noncrystallographic symmetry may assist in the design of containers made from DNA for applications in nanotechnology.


Grayson, N., Taormina, A., & Twarock, R. (2009). DNA duplex cage structures with icosahedral symmetry. Theoretical Computer Science, 410(15), 1440-1447.

Journal Article Type Article
Publication Date Apr 1, 2009
Deposit Date Feb 9, 2011
Publicly Available Date May 2, 2013
Journal Theoretical Computer Science
Print ISSN 0304-3975
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 410
Issue 15
Pages 1440-1447
Keywords Bionanotechnology, Synthetic DNA cage, Icosahedral symmetry.


Accepted Journal Article (265 Kb)

Copyright Statement
NOTICE: this is the author’s version of a work that was accepted for publication in Theoretical computer science. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Theoretical computer science, 411 (15), 2009, 10.1016/j.tcs.2008.12.005

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