Stable Polymorphs Crystallized Directly under Thermodynamic Control in Three-Dimensional Nanoconfinement: A Generic Methodology

Nicholson, CE; Chen, C; Mendis, B; Cooper, SJ

Abstract

Thermodynamic control of crystallization has been achieved to produce stable polymorphs directly by using three-dimensional (3D) nanoconfinement in microemulsions. The theoretical basis for thermodynamic control of crystallization using 3D nanoconfinement is outlined. The generality of our approach is demonstrated by crystallizing the stable polymorph of three “problem” compounds from microemulsions under conditions yielding metastable forms in bulk solution.

Citation

Nicholson, C., Chen, C., Mendis, B., & Cooper, S. (2011). Stable Polymorphs Crystallized Directly under Thermodynamic Control in Three-Dimensional Nanoconfinement: A Generic Methodology. Crystal Growth and Design, 11(2), 363-366. https://doi.org/10.1021/cg101200f

• Journal Article Type: Article
• Online Publication Date: Jan 5, 2011
• Publication Date: Jan 5, 2011
• Deposit Date: Jan 30, 2012
• Publicly Available Date: Sep 12, 2017
• Journal: Crystal Growth and Design
• Print ISSN: 1528-7483
• Electronic ISSN: 1528-7505
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 11
• Issue: 2
• Pages: 363-366
• DOI: https://doi.org/10.1021/cg101200f
• Public URL: https://durham-repository.worktribe.com/output/1519474