Investigating the Anti-leishmanial Effects of Linear Peptoids

Eggimann, G.A.; Bolt, H.L.; Denny, P.W.; Cobb, S.L.

Abstract

Peptoids, a class of peptide mimetics, have emerged as promising anti-infective agents against a range of bacterial infections. Herein we present the first study of the antiparasitic and specifically the anti-leishmanial properties of linear peptoids. Peptoids were identified as having promising activity against Leishmania mexicana axenic amastigotes, a causative agent of cutaneous leishmaniasis.

Citation

Eggimann, G., Bolt, H., Denny, P., & Cobb, S. (2015). Investigating the Anti-leishmanial Effects of Linear Peptoids. ChemMedChem, 10(3), 233-237. https://doi.org/10.1002/cmdc.201402416

• Journal Article Type: Article
• Acceptance Date: Dec 18, 2014
• Online Publication Date: Dec 15, 2014
• Publication Date: 2015-02
• Deposit Date: Dec 18, 2014
• Journal: ChemMedChem
• Print ISSN: 1860-7179
• Electronic ISSN: 1860-7187
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 3
• Pages: 233-237
• DOI: https://doi.org/10.1002/cmdc.201402416
• Keywords: Anti-leishmanial agents, Antiparasitic agents, Leishmania, Peptoids.
• Public URL: https://durham-repository.worktribe.com/output/1447968