A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles

Baxendale, Ian R.; Buckle, Christopher D.; Ley, Steven V.; Tamborini, Lucia

Abstract

Tosyl isocyanide and ethyl chloroformate react with nitrostyrenes to afford nitro-substituted pyrroles in good yield when a catch-and-release protocol was employed as a purification strategy.

Citation

Baxendale, I. R., Buckle, C. D., Ley, S. V., & Tamborini, L. (2009). A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles. Synthesis: Journal of Synthetic Organic Chemistry, 1485-1493. https://doi.org/10.1055/s-0028-1087991

• Journal Article Type: Article
• Acceptance Date: Feb 6, 2009
• Online Publication Date: Mar 6, 2009
• Publication Date: 2009-05
• Deposit Date: Jul 14, 2014
• Journal: Synthesis : journal of synthetic organic chemistry.
• Print ISSN: 0039-7881
• Electronic ISSN: 1437-210X
• Publisher: Thieme Gruppe
• Peer Reviewed: Peer Reviewed
• Issue: 9
• Pages: 1485-1493
• DOI: https://doi.org/10.1055/s-0028-1087991
• Public URL: https://durham-repository.worktribe.com/output/1447872