Robert M. Edkins
Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation
Edkins, Robert M.; Hayden, Elliott; Steed, Jonathan W.; Fucke, Katharina
Abstract
Two tetrahydocarbazolone derivatives were found to show multiple unsolvated crystal forms. A persistent dimer motif was detected in solution by FTIR spectroscopy that is maintained in the kinetic crystal forms. Rationally introduced steric bulk induces the formation of a more stable catemeric form.
Citation
Edkins, R. M., Hayden, E., Steed, J. W., & Fucke, K. (2015). Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation. Chemical Communications, 51(25), 5314-5317. https://doi.org/10.1039/c4cc10453f
| Journal Article Type | Article |
|---|---|
| Acceptance Date | Feb 10, 2015 |
| Publication Date | Mar 28, 2015 |
| Deposit Date | Mar 2, 2015 |
| Publicly Available Date | Mar 9, 2015 |
| Journal | Chemical Communications |
| Print ISSN | 1359-7345 |
| Electronic ISSN | 1364-548X |
| Publisher | Royal Society of Chemistry |
| Peer Reviewed | Peer Reviewed |
| Volume | 51 |
| Issue | 25 |
| Pages | 5314-5317 |
| DOI | https://doi.org/10.1039/c4cc10453f |
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