Skip to main content

Research Repository

Advanced Search

Furosemide Cocrystals: Structures, Hydrogen Bonding, and Implications for Properties

Harriss, Bethany I.; Vella-Zarb, Liana; Wilson, Claire; Radosavljevic Evans, Ivana

Furosemide Cocrystals: Structures, Hydrogen Bonding, and Implications for Properties Thumbnail


Authors

Bethany I. Harriss

Liana Vella-Zarb

Claire Wilson

Ivana Radosavljevic Evans



Contributors

Abstract

Four new crystal structures of pharmaceutical molecule furosemide with GRAS coformers are reported and correlated with the known pharmacologically relevant properties of these materials. Furosemide carboxylic acid oxygen donor−coformer aromatic nitrogen acceptor is the dominant synthon, leading to the key intermolecular interactions in the cocrystals studied.

Citation

Harriss, B. I., Vella-Zarb, L., Wilson, C., & Radosavljevic Evans, I. (2014). Furosemide Cocrystals: Structures, Hydrogen Bonding, and Implications for Properties. Crystal Growth and Design, 14(2), 783-791. https://doi.org/10.1021/cg401662d

Journal Article Type Article
Publication Date Feb 5, 2014
Deposit Date Oct 21, 2014
Publicly Available Date Jan 28, 2015
Journal Crystal Growth and Design
Print ISSN 1528-7483
Electronic ISSN 1528-7505
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 14
Issue 2
Pages 783-791
DOI https://doi.org/10.1021/cg401662d

Files

Accepted Journal Article (2 Mb)
PDF

Copyright Statement
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Crystal growth and design, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://dx.doi.org/10.1021/cg401662d







You might also like



Downloadable Citations