EuroTracker® dyes : design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging
Butler, S.J.; Delbianco, M.; Lamarque, L.; McMahon, B.K.; Neil, E.R.; Pal, R.; Parker, D.; Walton, J.W.; Zwier, J.
Professor Robert Pal email@example.com
Professor David Parker firstname.lastname@example.org
Dr James Walton email@example.com
The development of the brightest luminescent europium(III) complexes is traced, including analysis of the C3-symmetric core complex based on a functionalized triazacyclononane and identification of the most suitable strongly absorbing chromophore. Strategies for the synthesis of the complexes, including enantiopure analogues, are outlined and opportunities for applications in time-resolved microscopy and spectral imaging emphasised. Practicable examples are introduced, including selective organelle staining for cellular optical imaging at 65 nm resolution and the development of new bioassays using time-resolved FRET methods.
Butler, S., Delbianco, M., Lamarque, L., McMahon, B., Neil, E., Pal, R., …Zwier, J. (2015). EuroTracker® dyes : design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging. Dalton Transactions, 44(11), 4791-4803. https://doi.org/10.1039/c4dt02785j
|Journal Article Type||Article|
|Acceptance Date||Oct 10, 2014|
|Online Publication Date||Oct 13, 2014|
|Publication Date||Mar 21, 2015|
|Deposit Date||Nov 14, 2014|
|Publicly Available Date||Nov 20, 2014|
|Publisher||Royal Society of Chemistry|
|Peer Reviewed||Peer Reviewed|
Accepted Journal Article