Modeling transversely isotropic, viscoelastic, incompressible tissue-like materials with application in ultrasound shear wave elastography

Qiang, Bo; Brigham, John C.; Aristizabal, Sara; Greenleaf, James F.; Zhang, Xiaoming; Urban, Matthew W.

Abstract

In this paper, we propose a method to model the shear wave propagation in transversely isotropic, viscoelastic and incompressible media. The targeted application is ultrasound-based shear wave elastography for viscoelasticity measurements in anisotropic tissues such as the kidney and skeletal muscles. The proposed model predicts that if the viscoelastic parameters both across and along fiber directions can be characterized as a Voigt material, then the spatial phase velocity at any angle is also governed by a Voigt material model. Further, with the aid of Taylor expansions, it is shown that the spatial group velocity at any angle is close to a Voigt type for weakly attenuative materials within a certain bandwidth. The model is implemented in a finite element code by a time domain explicit integration scheme and shear wave simulations are conducted. The results of the simulations are analyzed to extract the shear wave elasticity and viscosity for both the spatial phase and group velocities. The estimated values match well with theoretical predictions. The proposed theory is further verified by an ex vivo tissue experiment measured in a porcine skeletal muscle by an ultrasound shear wave elastography method. The applicability of the Taylor expansion to analyze the spatial velocities is also discussed. We demonstrate that the approximations from the Taylor expansions are subject to errors when the viscosities across or along the fiber directions are large or the maximum frequency considered is beyond the bandwidth defined by radii of convergence of the Taylor expansions.

Citation

Qiang, B., Brigham, J. C., Aristizabal, S., Greenleaf, J. F., Zhang, X., & Urban, M. W. (2015). Modeling transversely isotropic, viscoelastic, incompressible tissue-like materials with application in ultrasound shear wave elastography. Physics in Medicine & Biology, 60(3), 1289-1306. https://doi.org/10.1088/0031-9155/60/3/1289

• Journal Article Type: Article
• Acceptance Date: Nov 20, 2014
• Online Publication Date: Jan 16, 2015
• Publication Date: Feb 7, 2015
• Deposit Date: May 13, 2016
• Publicly Available Date: Jun 4, 2018
• Journal: Physics in Medicine and Biology
• Print ISSN: 0031-9155
• Electronic ISSN: 1361-6560
• Publisher: IOP Publishing
• Peer Reviewed: Peer Reviewed
• Volume: 60
• Issue: 3
• Pages: 1289-1306
• DOI: https://doi.org/10.1088/0031-9155/60/3/1289
• Public URL: https://durham-repository.worktribe.com/output/1404616
• Related Public URLs: https://www.ncbi.nlm.nih.gov/pubmed/25591921