EM∩IM: Software for relating ion mobility mass spectrometry and electron microscopy data

Degiacomi, M.T.; Benesch, J.L.P.

Abstract

We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.

Citation

Degiacomi, M., & Benesch, J. (2016). EM∩IM: Software for relating ion mobility mass spectrometry and electron microscopy data. Analyst, 141(1), 70-75. https://doi.org/10.1039/c5an01636c

• Journal Article Type: Article
• Acceptance Date: Nov 23, 2015
• Online Publication Date: Nov 23, 2015
• Publication Date: Jan 7, 2016
• Deposit Date: Jul 26, 2017
• Publicly Available Date: Aug 8, 2017
• Journal: Analyst
• Print ISSN: 0003-2654
• Electronic ISSN: 1364-5528
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 141
• Issue: 1
• Pages: 70-75
• DOI: https://doi.org/10.1039/c5an01636c
• Public URL: https://durham-repository.worktribe.com/output/1380947