Exploring Flow Procedures for Diazonium Formation

Hu, T.; Baxendale, I.R.; Baumann, M.

Abstract

The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption.

Citation

Hu, T., Baxendale, I., & Baumann, M. (2016). Exploring Flow Procedures for Diazonium Formation. Molecules, 21(7), Article 918. https://doi.org/10.3390/molecules21070918

• Journal Article Type: Article
• Acceptance Date: Jul 5, 2016
• Online Publication Date: Jul 14, 2016
• Publication Date: Jul 14, 2016
• Deposit Date: Jul 14, 2016
• Publicly Available Date: Jul 20, 2016
• Journal: Molecules
• Electronic ISSN: 1420-3049
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 21
• Issue: 7
• Article Number: 918
• DOI: https://doi.org/10.3390/molecules21070918
• Public URL: https://durham-repository.worktribe.com/output/1379579