High Pressure/Low Temperature Polymorphism in 2,6-Dimethylpyridine–Formic Acid Cocrystals

Lee, Rachael; Yufit, Dmitry S.; Probert, Michael R.; Steed, Jonathan W.

Abstract

Five new cocrystals of 2,6-dimethylpyridine (DMP) with formic acid (FA) were crystallized by application of pressure in a diamond anvil cell and by in situ cryo-crystallization. Mixtures in ratios 1:1, 1:2, and 1:3 of DMP–FA have crystallized via both methods. Both the 1:2 and 1:3 cocrystals exhibit high pressure/low temperature polymorphism.

Citation

Lee, R., Yufit, D. S., Probert, M. R., & Steed, J. W. (2017). High Pressure/Low Temperature Polymorphism in 2,6-Dimethylpyridine–Formic Acid Cocrystals. Crystal Growth and Design, 17(4), 1647-1653. https://doi.org/10.1021/acs.cgd.6b01656

• Journal Article Type: Article
• Acceptance Date: Feb 28, 2017
• Online Publication Date: Mar 1, 2017
• Publication Date: Apr 15, 2017
• Deposit Date: Apr 27, 2017
• Publicly Available Date: Mar 1, 2018
• Journal: Crystal Growth and Design
• Print ISSN: 1528-7483
• Electronic ISSN: 1528-7505
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 4
• Pages: 1647-1653
• DOI: https://doi.org/10.1021/acs.cgd.6b01656
• Public URL: https://durham-repository.worktribe.com/output/1359300