Exploiting C-H Borylation for the Multidirectional Elaboration of 2-Halopyridines

Reuven, J.A.; Salih, O.A.; Sadler, S.A.; Thomas, C.L.; Steel, P.G.

Abstract

Regioselectively polysubstituted pyridines can be efficiently accessed from 2-halopyridines via a sequence involving C-H borylation, Suzuki-Miyaura cross-coupling and nucleophilic aromatic substitution chemistry.

Citation

Reuven, J., Salih, O., Sadler, S., Thomas, C., & Steel, P. (2020). Exploiting C-H Borylation for the Multidirectional Elaboration of 2-Halopyridines. Tetrahedron, 76(3), Article 130836. https://doi.org/10.1016/j.tet.2019.130836

• Journal Article Type: Article
• Acceptance Date: Nov 25, 2019
• Online Publication Date: Nov 29, 2019
• Publication Date: Jan 17, 2020
• Deposit Date: Nov 26, 2019
• Publicly Available Date: Nov 29, 2020
• Journal: Tetrahedron
• Print ISSN: 0040-4020
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 76
• Issue: 3
• Article Number: 130836
• DOI: https://doi.org/10.1016/j.tet.2019.130836