Crystal habit modification of Cu(ii) isonicotinate–N-oxide complexes using gel phase crystallisation

Ghosh, Dipankar; Ferfolja, Katja; Drabavičius, Žygimantas; Steed, Jonathan W.; Damodaran, Krishna K.

Abstract

We report the crystallisation of three forms of the copper(II) isonicotinate–N-oxide complex and their phase interconversion via solvent-mediated crystal-to-crystal transformation. The different forms of the copper complex have been isolated and characterised by single crystal X-ray diffraction. Gel phase crystallisation performed in hydrogels, low molecular weight gels and gels of a tailored gelator showed crystal habit modification. Crystallisation in aqueous ethanol resulted in the concomitant formation of blue (form-I) and green (form-II/IV) crystals while the use of a low molecular weight gel resulted in the selective crystallization of the blue form-I under identical conditions. Comparison of the gel phase and the solution state crystallisation in various solvent compositions reveals that the blue form-I is the thermodynamically stable form under ambient conditions.

Citation

Ghosh, D., Ferfolja, K., Drabavičius, Ž., Steed, J. W., & Damodaran, K. K. (2018). Crystal habit modification of Cu(ii) isonicotinate–N-oxide complexes using gel phase crystallisation. New Journal of Chemistry, 42(24), 19963-19970. https://doi.org/10.1039/c8nj05036h

• Journal Article Type: Article
• Acceptance Date: Nov 1, 2018
• Online Publication Date: Nov 2, 2018
• Publication Date: Dec 21, 2018
• Deposit Date: Dec 14, 2018
• Publicly Available Date: Nov 1, 2019
• Journal: New Journal of Chemistry
• Print ISSN: 1144-0546
• Electronic ISSN: 1369-9261
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 42
• Issue: 24
• Pages: 19963-19970
• DOI: https://doi.org/10.1039/c8nj05036h
• Public URL: https://durham-repository.worktribe.com/output/1311713