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Ratifying frailty

Moreira, Tiago

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Taking as a point of departure the role that the category of frailty increasingly plays in the classification, sorting and management of ageing populations in contemporary societies, this paper focuses on the crafting and validation of mouse models of frailty. The paper suggests that such models embody therapeutic and techno-economic expectations of ageing research, particularly as these are re-invigorated by current attempts to manipulate or eradicate cell senescence. The paper brings together critical gerontology, social studies of science and more-than-human anthropology to contextualise and analyse ethnographic data collected during fieldwork in a biology of ageing laboratory. The paper proposes that to build a mouse model of frailty, researchers need to learn to ‘think like a mouse’, provisionally taking the animal's point of view, to then efface that link and reconfigure the scientific chain of reference that enables translation between humans and mouse models of frailty.


Moreira, T. (2022). Ratifying frailty. Journal of Aging Studies, 62, Article 101055.

Journal Article Type Article
Acceptance Date Jun 20, 2022
Online Publication Date Jul 8, 2022
Publication Date 2022
Deposit Date Aug 1, 2022
Publicly Available Date Aug 1, 2022
Journal Journal of Aging Studies
Print ISSN 0890-4065
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 62
Article Number 101055


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