Molecular clusters in confined spaces

Braschinsky, Alan; Steed, Jonathan W.

Abstract

Confinement chemistry is a growing field with many potential applications in the synthetic, catalytic and especially pharmaceutical industries. Confinement of materials can reveal novel properties as compared to their bulk. They can also give insight into the nucleation and crystallization processes at the nanoscale. In this review, we focus on enclosed molecular clusters, from small aggregates to nucleation effects and ultimately crystallization within confining matrices such as metal–organic frameworks (MOFs), discrete cages, nanopores and droplets ranging from 5 Å to 2 mm. This review aims to impact on the discovery of new drug solid forms, drug delivery, crystal engineering, water harvesting, and gas capture among other topics.

Citation

Braschinsky, A., & Steed, J. W. (2022). Molecular clusters in confined spaces. Coordination Chemistry Reviews, 473, https://doi.org/10.1016/j.ccr.2022.214840

• Journal Article Type: Article
• Acceptance Date: Sep 9, 2022
• Online Publication Date: Sep 24, 2022
• Publication Date: 2022-12
• Deposit Date: Oct 26, 2022
• Publicly Available Date: Oct 26, 2022
• Journal: Coordination Chemistry Reviews
• Print ISSN: 0010-8545
• Electronic ISSN: 1873-3840
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 473
• DOI: https://doi.org/10.1016/j.ccr.2022.214840
• Public URL: https://durham-repository.worktribe.com/output/1187503