Going Full Circle with Organocatalysis and Biocatalysis: The Latent Potential of Cofactor Mimics in Asymmetric Synthesis
Murray, Jacob; Hodgson, David R.W.; O’Donoghue, AnnMarie C.
Professor David Hodgson firstname.lastname@example.org
Professor Ann O'Donoghue email@example.com
Many enzymes work in tandem with small molecule cofactors, which have inspired organocatalyst designs. Chemical modification of cofactor scaffolds has increased organocatalytic reactivity and reaction scope. This synopsis presents a selection of recent advances in the use of cofactors (native and mimics) in organocatalysis and biocatalysis. We aim to highlight the benefits of combining fundamental knowledge gained in both bio- and organo-catalysis for asymmetric biocatalysis.
Murray, J., Hodgson, D. R., & O’Donoghue, A. C. (in press). Going Full Circle with Organocatalysis and Biocatalysis: The Latent Potential of Cofactor Mimics in Asymmetric Synthesis. Journal of Organic Chemistry, https://doi.org/10.1021/acs.joc.2c02747
|Journal Article Type||Article|
|Online Publication Date||Apr 26, 2023|
|Deposit Date||May 16, 2023|
|Publicly Available Date||May 16, 2023|
|Journal||The Journal of Organic Chemistry|
|Publisher||American Chemical Society|
|Peer Reviewed||Peer Reviewed|
Published Journal Article
Publisher Licence URL
This work is licensed under a Creative Commons Attribution 4.0 International License.
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