Fine control of metal concentrations is necessary for cells to discern zinc from cobalt
(2017)
Journal Article
Osman, D., Foster, A. W., Chen, J., Svedaite, K., Steed, J. W., Lurie-Luke, E., …Robinson, N. J. (2017). Fine control of metal concentrations is necessary for cells to discern zinc from cobalt. Nature Communications, 8, Article 1884. https://doi.org/10.1038/s41467-017-02085-z
Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific metals, but metal binding is not specific in vitro. Here we show that tight regulation of buffered intracellular metal concentrations is a prerequis... Read More about Fine control of metal concentrations is necessary for cells to discern zinc from cobalt.