Outputs (7)

Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial (2024)
Journal Article
Austin, D., Maier, R. H., Akhter, N., Sayari, M., Ogundimu, E., Maddox, J. M., Vahabi, S., Humphreys, A. C., Graham, J., Oxenham, H., Haney, S., Cresti, N., Verrill, M., Osborne, W., Wright, K. L., Goranova, R., Bailey, J. R., Kalakonda, N., Macheta, M., Kilner, M. F., …Plummer, C. (2024). Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial. Journal of the American College of Cardiology, 6(5), 684-696. https://doi.org/10.1016/j.jaccao.2024.07.010

Background
Cardiotoxicity is a concern for cancer survivors undergoing anthracycline chemotherapy. Enalapril has been explored for its potential to mitigate cardiotoxicity in cancer patients. The dose-dependent cardiotoxicity effec... Read More about Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial.

Nationally Automated Colonoscopy Performance Feedback Increases Polyp Detection: the NED APRIQOT Randomised Controlled Trial. (2024)
Journal Article
Catlow, J., Sharp, L., Wagnild, J., Lu, L., Bhardwaj-Gosling, R., Ogundimu, E., Kasim, A., Brookes, M., Lee, T., McCarthy, S., Gray, J., Sniehotta, F., Valori, R., Westwood, C., McNally, R., Ruwende, J., Sinclair, S., Deane, J., & Rutter, M. (2024). Nationally Automated Colonoscopy Performance Feedback Increases Polyp Detection: the NED APRIQOT Randomised Controlled Trial. Clinical Gastroenterology and Hepatology, 22(9), 1926-1936. https://doi.org/10.1016/j.cgh.2024.03.048

Post-colonoscopy colorectal cancer incidence and mortality rates are higher for endoscopists with low polyp detection rates. Using the UK's National Endoscopy Database (NED), which automatically captures real-time data, we assessed if providing feedb... Read More about Nationally Automated Colonoscopy Performance Feedback Increases Polyp Detection: the NED APRIQOT Randomised Controlled Trial..

Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol (2023)
Journal Article
Akowuah, E., Mathias, A., Bardgett, M., Harrison, S., Kasim, A. S., Loughran, K., Ogundimu, E., Trevis, J., Wagnild, J., Witharana, P., Hancock, H. C., & Maier, R. H. (2023). Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol. BMJ Open, 13(1), Article e065992. https://doi.org/10.1136/+bmjopen-2022-065992

Introduction: Prehabilitation prior to surgery has been shown to reduce postoperative complications, reduce length of hospital stay and improve quality of life after cancer and limb reconstruction surgery. However, there are minimal data on the impac... Read More about Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (THE PrEPS TRIAL) – a study protocol.

Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT) (2022)
Journal Article
Maier, R. H., Plummer, C., Kasim, A. S., Akhter, N., Ogundimu, E., Maddox, J., Graham, J., Stewart, M., Wardley, A., Haney, S., Vahabi, S., Oxenham, H., Humphreys, A., Cresti, N., Verrill, M., Graham, R., Chang, L., Hancock, H. C., & Austin, D. (2022). Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT). BMJ Open, 12(12), Article e066252. https://doi.org/10.1136/bmjopen-2022-066252

Introduction: Anthracyclines are included in chemotherapy regimens to treat several different types of cancer and are extremely effective. However, it is recognised that a significant side effect is cardiotoxicity; anthracyclines can cause irreversib... Read More about Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT).

Individual Participant Data Meta-analysis of the Impact of Educational Interventions on Pupils Eligible for Free School Meals (2021)
Journal Article
Ashraf, B., Singh, A., Uwimpuhwe, G., Higgins, S., & Kasim, A. (2021). Individual Participant Data Meta-analysis of the Impact of Educational Interventions on Pupils Eligible for Free School Meals. British Educational Research Journal, 47(6), 1675-1699. https://doi.org/10.1002/berj.3749

Meta-analysis is the synthesis of findings from research projects, which enables an estimate of the average or pooled effect across various studies. This study presents findings from the intention to treat analysis for a series of educational evaluat... Read More about Individual Participant Data Meta-analysis of the Impact of Educational Interventions on Pupils Eligible for Free School Meals.

Individual-participant-data-meta-analysis-of-the-impact-of-EEF-trials-on-the-educational-attainment-of-pupils-on-Free-School-Meals (2021)
Report
Ashraf, B., Singh, A., Uwimpuhwe, G., Coolen-Maturi, T., Einbeck, J., Higgins, S., & Kasim, A. (2021). Individual-participant-data-meta-analysis-of-the-impact-of-EEF-trials-on-the-educational-attainment-of-pupils-on-Free-School-Meals. EEF

Multisite educational trials: estimating the effect size and its confidence intervals (2021)
Journal Article
Singh, A., Uwimpuhwe, G., Li, M., Einbeck, J., Higgins, S., & Kasim, A. (2022). Multisite educational trials: estimating the effect size and its confidence intervals. International Journal of Research & Method in Education, 45(1), 18-38. https://doi.org/10.1080/1743727x.2021.1882416

In education, multisite trials involve randomisation of pupils into intervention and comparison groups within schools. Most analytical models in multisite educational trials ignore that the impact of an intervention may be school dependent. This stud... Read More about Multisite educational trials: estimating the effect size and its confidence intervals.