Outputs (10)

Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy (2013)
Journal Article
Bourgenot, C., Saunter, C., Love, G., & Girkin, J. (2013). Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy. Journal of the European Optical Society-Rapid Publications, 8, Article 13027. https://doi.org/10.2971/jeos.2013.13027

We report on a closed loop widefield adaptive optics, optical microscopy system in which the feedback signal is provided by backscattered light from the sample acting as a guide star. The improvement in imaging performance is compared to an adaptive... Read More about Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy.

3D adaptive optics in a light sheet microscope (2012)
Journal Article
Bourgenot, C., Saunter, C. D., Taylor, J. M., Girkin, J. M., & Love, G. D. (2012). 3D adaptive optics in a light sheet microscope. Optics Express, 20(12), 13252-13261. https://doi.org/10.1364/oe.20.013252

We report on a single plane illumination microscope (SPIM) incorporating adaptive optics in the imaging arm. We show how aberrations can occur from the sample mounting tube and quantify the aberrations both experimentally and computationally. A wavef... Read More about 3D adaptive optics in a light sheet microscope.

Adaptive optical methods for in vivo imaging in developing Zebra fish
Presentation / Conference Contribution
Girkin, J., Taylor, J., Bourgenot, C., Saunter, C., & Love, G. (2012, December). Adaptive optical methods for in vivo imaging in developing Zebra fish. Presented at 2012 International Symposium on Optomechatronic Technologies (ISOT 2012), Paris

The humble Zebra fish is rapidly establishing itself as the model of choice for a wide range of biological investigations, in particular at the developing embryo stage. Single Plane Illumination Microscopy (SPIM) has already been shown to be a very p... Read More about Adaptive optical methods for in vivo imaging in developing Zebra fish.

AO modal optimization in a live, beating zebrafish heart
Presentation / Conference Contribution
Bourgenot, C., Taylor, J. M., Saunter, C. D., Girkin, J. M., & Love, G. D. (2013, June). AO modal optimization in a live, beating zebrafish heart. Presented at Imaging and Applied Optics Postdeadline, Arlington, Virginia, United States

We report on the combinated use of heart synchronization and wavefront sensorless modal AO to enable significant improvement in image quality of a live transgenic zebrafish embryo heart, imaged with a light sheet microscope.

Wide field adaptive optics microscopy using both closed loop correction and image sharpness optimization
Presentation / Conference Contribution
Bourgenot, C., Love, G. D., Saunter, C. D., & Girkin, J. M. (2011, July). Wide field adaptive optics microscopy using both closed loop correction and image sharpness optimization. Presented at Imaging and Applied Optics, Toronto, Canada

We report on results from a wide field microscope fitted with adaptive optics. We describe results based on both image optimization (wavefront sensorless adaptive optics) and full closed loop correction.

Light sheet adaptive optics microscope for 3D live imaging
Presentation / Conference Contribution
Bourgenot, C., Taylor, J., Saunter, C., Girkin, J., & Love, G. (2013, February). Light sheet adaptive optics microscope for 3D live imaging. Presented at Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XX, San Francisco, California, USA

We report on the incorporation of adaptive optics (AO) into the imaging arm of a selective plane illumination microscope (SPIM). SPIM has recently emerged as an important tool for life science research due to its ability to deliver high-speed, optica... Read More about Light sheet adaptive optics microscope for 3D live imaging.

Closed loop adaptive optics with a laser guide star for biological light microscopy
Presentation / Conference Contribution
Saunter, C. D., Bourgenot, C., Girkin, J. M., & Love, G. D. (2012, January). Closed loop adaptive optics with a laser guide star for biological light microscopy. Presented at MEMS Adaptive Optics VI, San Francisco, CA

We report on the development of a widefield microscope that achieves adaptive optics correction through the use of a wavefront sensor observing an artificial laser guide star induced within the sample. By generating this guide star at arbitrary posit... Read More about Closed loop adaptive optics with a laser guide star for biological light microscopy.

Realtime wavefront sensing in a SPIM microscope, and active aberration tracking
Presentation / Conference Contribution
Taylor, J. M., Saunter, C. D., Bourgenot, C., Girkin, J. M., & Love, G. D. (2015, February). Realtime wavefront sensing in a SPIM microscope, and active aberration tracking. Presented at Adaptive Optics and Wavefront Control for Biological Systems, San Francisco, CA

Adaptive optics (AO) can potentially allow high resolution imaging deep inside living tissue, mitigating against the loss of resolution due to aberrations caused by overlying tissue. Closed-loop AO correction is particularly attractive for moving tis... Read More about Realtime wavefront sensing in a SPIM microscope, and active aberration tracking.

Adaptive optics for wide-field microscopy
Presentation / Conference Contribution
Bourgenot, C., Saunter, C., Girkin, J., & Love, G. (2011, January). Adaptive optics for wide-field microscopy. Presented at Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVIII, San Francisco, CA

We report on recent developments in the use of adaptive optics (AO) in wide-field microscopy to remove both system and sample induced aberrations. We describe progress on using both a full AO system and image optimization techniques (wavefront sensor... Read More about Adaptive optics for wide-field microscopy.

Design, manufacture, and evaluation of prototype telescope windows for use in low-vision aids
Presentation / Conference Contribution
Young, L., Robertson, D., Love, G., Girkin, J., Cowie, E., Bourgenot, C., & Courtial, J. (2017, November). Design, manufacture, and evaluation of prototype telescope windows for use in low-vision aids. Presented at Novel Optical Systems Design and Optimization XX, San Diego, California

Pixellated Optics, a class of optical devices which preserve phase front continuity only over small sub areas of the device, allow for a range of uses that would not otherwise be possible. One potential use is as Low Vision Aids (LVAs), where they ar... Read More about Design, manufacture, and evaluation of prototype telescope windows for use in low-vision aids.