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Neutron reflectivity studies at liquid-liquid interfaces: Methodology and analysis (2001)
Journal Article
Bowers, J., Zarbakhsh, A., Webster, J., Hutchings, L., & Richards, R. (2001). Neutron reflectivity studies at liquid-liquid interfaces: Methodology and analysis. Langmuir, 17(1), 140-145

A protocol is described for measuring and analyzing neutron reflectivity data from a buried oil-water interface. A hexadecane-water interface is considered, and data from the bare interface and from films of polybutadiene-poly(ethylene oxide) Linear... Read More about Neutron reflectivity studies at liquid-liquid interfaces: Methodology and analysis.

Small-angle neutron scattering from single arm labeled polybutadiene star polymers in dilute solution (2001)
Journal Article
Hutchings, L., Richards, R., Reynolds, S., & Thompson, R. (2001). Small-angle neutron scattering from single arm labeled polybutadiene star polymers in dilute solution. Macromolecules, 34(16), 5571-5578

Dilute cyclohexane solutions of polybutadiene star polymers with 3, 4, 8, and 12 arms wherein one arm is perdeuterated have been investigated by small-angle neutron scattering. The scattering cross sections obtained showed a characteristic peak at fi... Read More about Small-angle neutron scattering from single arm labeled polybutadiene star polymers in dilute solution.

The first thousand-molecule simulation of a mesogen at the fully atomistic level (2001)
Journal Article
CookM.R. Wilson, M. (2001). The first thousand-molecule simulation of a mesogen at the fully atomistic level. Molecular Crystals and Liquid Crystals, 363, 181-+

The first thousand-molecule atomistic simulation of a mesogenic system is described. The simulations involve a study of the mesogen 4-(trans-4-n-pentylcyclohexyl) benzonitrile (PCH5) in the isotropic phase, close to the phase transition to a nematic... Read More about The first thousand-molecule simulation of a mesogen at the fully atomistic level.

Molecular models in computer simulation of liquid crystals (2001)
Journal Article
IlnytskyiM.R. Wilson, J. (2001). Molecular models in computer simulation of liquid crystals. Journal of Molecular Liquids, 92(1-2), 21-28

A brief historical survey of progress in computer simulations of liquid crystal phases is provided. We stress the main ideas and developments in the field, concentrating on three different levels of molecular modelling: lattice models, soft nonspheri... Read More about Molecular models in computer simulation of liquid crystals.

Narrow-range optical pH sensors based on luminescent europium and terbium complexes immobilized in a sol gel glass (2001)
Journal Article
Blair, S., Lowe, M., Mathieu, C., Parker, D., Senanayake, P., & Kataky, R. (2001). Narrow-range optical pH sensors based on luminescent europium and terbium complexes immobilized in a sol gel glass. Inorganic Chemistry, 40(23), 5860-5867

The metal-based emission of a series of luminescent europium and terbium complexes incorporating an aromatic chromophore is rendered pH-dependent either through perturbation of the aryl singlet or triplet energy or by modulating the degree of quenchi... Read More about Narrow-range optical pH sensors based on luminescent europium and terbium complexes immobilized in a sol gel glass.

The effect of morphology upon mobility: Implications for bulk heterojunction solar cells with nonuniform blend morphology (2009)
Journal Article
Groves, C., Koster, L., & Greenham, N. (2009). The effect of morphology upon mobility: Implications for bulk heterojunction solar cells with nonuniform blend morphology. Journal of Applied Physics, 105(9), https://doi.org/10.1063/1.3117493

We use a Monte Carlo model to predict the effect of composition, domain size, and energetic disorder upon the mobility of carriers in an organic donor-acceptor blend. These simulations show that, for the changes in local morphology expected within th... Read More about The effect of morphology upon mobility: Implications for bulk heterojunction solar cells with nonuniform blend morphology.

Capillary wave properties of a spread film of a polybutadiene- poly(ethylene oxide) block copolymer: 2. Cyclohexane-water interface. (2001)
Journal Article
Milling, A., Hutchings, L., & Richards, R. (2001). Capillary wave properties of a spread film of a polybutadiene- poly(ethylene oxide) block copolymer: 2. Cyclohexane-water interface. Langmuir, 17(17), 5305-5313. https://doi.org/10.1021/la010324g

A diblock copolymer of polybutadiene and poly(ethylene oxide) has been spread at the interface between cyclohexane and water, and the properties of the capillary waves were determined by light scattering. As the concentration of block copolymer at th... Read More about Capillary wave properties of a spread film of a polybutadiene- poly(ethylene oxide) block copolymer: 2. Cyclohexane-water interface..

Development of an all-atom force field for the simulation of liquid crystal molecules in condensed phases (LCFF) (2001)
Journal Article
CookM.R. Wilson, M. (2001). Development of an all-atom force field for the simulation of liquid crystal molecules in condensed phases (LCFF). Molecular Crystals and Liquid Crystals, 357, 149-165

A set of intermolecular potential energy functions have been developed for use in computer simulations of mesogenic molecules in the isotropic and liquid crystalline phases. Primarily. the force field parameters have been developed for the mesogens G... Read More about Development of an all-atom force field for the simulation of liquid crystal molecules in condensed phases (LCFF).

A domain decomposition molecular dynamics program for the simulation of flexible molecules with an arbitrary topology of Lennard-Jones and/or Gay-Berne sites (2001)
Journal Article
Ilnytskyi, J., & Wilson, M. (2001). A domain decomposition molecular dynamics program for the simulation of flexible molecules with an arbitrary topology of Lennard-Jones and/or Gay-Berne sites. Computer Physics Communications, 134(1), 23-32. https://doi.org/10.1016/s0010-4655%2800%2900187-9

We describe a new parallel molecular dynamics program GBMOLDD which uses the domain decomposition algorithm. The program is designed to simulate molecular systems composed of both spherically-symmetric and anisotropic sites connected via arbitrary to... Read More about A domain decomposition molecular dynamics program for the simulation of flexible molecules with an arbitrary topology of Lennard-Jones and/or Gay-Berne sites.

The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives (2001)
Journal Article
Cooper, S. (2001). The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives. CrystEngComm, art. no.-56

L-Asparagine monohydrate crystals grown from 100-300% supersaturated solutions in the presence of 1-20 mg ml(-1) polyacrylic acid exhibit a needle-like morphology, instead of their normal prismatic morphology. A similar effect is observed for crystal... Read More about The effect of additive aggregation state on controlling crystallization. Crystallization of L-asparagine monohydrate in the presence of carboxylic acid functionality additives.

FGF-2 Release from the Lens Capsule by MMP-2 Maintains Lens Epithelial Cell Viability (2007)
Journal Article
Tholozan, F., Gribbon, C., Li, Z., Goldberg, M., Prescott, A., McKie, N., & Quinlan, R. (2007). FGF-2 Release from the Lens Capsule by MMP-2 Maintains Lens Epithelial Cell Viability. Molecular Biology of the Cell, 18(11), 4222-4231. https://doi.org/10.1091/mbc.e06-05-0416

The lens is an avascular tissue, separated from the aqueous and vitreous humors by its own extracellular matrix, the lens capsule. Here we demonstrate that the lens capsule is a source of essential survival factors for lens epithelial cells. Primary... Read More about FGF-2 Release from the Lens Capsule by MMP-2 Maintains Lens Epithelial Cell Viability.

Reorganization of centrosomal marker proteins coincides with epithelial cell differentiation in the vertebrate lens (2007)
Journal Article
Dahm, R., Procter, J., Ireland, M., Lo, W., Mogensen, M., Quinlan, R., & Prescott, A. (2007). Reorganization of centrosomal marker proteins coincides with epithelial cell differentiation in the vertebrate lens. Experimental Cell Research, 85(5), 696-713. https://doi.org/10.1016/j.exer.2007.07.022

The differentiation of epithelial cells in the vertebrate lens involves a series of changes that includes the degradation of all intracellular organelles and a dramatic elongation of the cells. The latter is accompanied by a substantial remodelling o... Read More about Reorganization of centrosomal marker proteins coincides with epithelial cell differentiation in the vertebrate lens.

Desmin aggregate formation by R120G alpha B-crystallin is caused by altered filament interactions and is dependent upon network status in cells (2004)
Journal Article
Perng, M., Wen, S., van den Ijssel, P., Prescott, A., & Quinlan, R. (2004). Desmin aggregate formation by R120G alpha B-crystallin is caused by altered filament interactions and is dependent upon network status in cells. Molecular Biology of the Cell, 15(5), 2335-2346. https://doi.org/10.1091/mbc.e03-12-0893

The R120G mutation in alphaB-crystallin causes desmin-related myopathy. There have been a number of mechanisms proposed to explain the disease process, from altered protein processing to loss of chaperone function. Here, we show that the mutation alt... Read More about Desmin aggregate formation by R120G alpha B-crystallin is caused by altered filament interactions and is dependent upon network status in cells.

The Alexander disease-causing Glial Fibrillary Acidic Protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alphaB-crystallin and HSP27 (2006)
Journal Article
Perng, M., Su, M., Wen, S., Li, R., Gibbon, T., Prescott, A., …Quinlan, R. (2006). The Alexander disease-causing Glial Fibrillary Acidic Protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alphaB-crystallin and HSP27. American Journal of Human Genetics, 79(2), 197-213. https://doi.org/10.1086/504411

Here, we describe the early events in the disease pathogenesis of Alexander disease. This is a rare and usually fatal neurodegenerative disorder whose pathological hallmark is the abundance of protein aggregates in astrocytes. These aggregates, terme... Read More about The Alexander disease-causing Glial Fibrillary Acidic Protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alphaB-crystallin and HSP27.

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract (2002)
Journal Article
Sandilands, A., Hutcheson, A., Long, H., Prescott, A., Vrensen, G., Löster, J., …Quinlan, R. (2002). Altered aggregation properties of mutant gamma-crystallins cause inherited cataract. The EMBO Journal, 21(22), 6005-6014. https://doi.org/10.1093/emboj/cdf609

Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key even... Read More about Altered aggregation properties of mutant gamma-crystallins cause inherited cataract.

The integrity of welded interfaces in ultra high molecular weight polyethylene: Part 1 Model (2006)
Journal Article
Buckley, C., Wu, J., & Haughie, D. (2006). The integrity of welded interfaces in ultra high molecular weight polyethylene: Part 1 Model. Biomaterials, 27(17), 3178-3186. https://doi.org/10.1016/j.biomaterials.2006.01.030

The difficulty of eradicating memory of powder–particle interfaces in UHMWPE for bearing surfaces for hip and knee replacements is well-known, and ‘fusion defects’ have been implicated frequently in joint failures. During processing the polymer is fo... Read More about The integrity of welded interfaces in ultra high molecular weight polyethylene: Part 1 Model.

Processing of ultra-high molecular weight polyethylene : modelling the decay of fusion defects (2002)
Journal Article
Wu, J., Buckley, C., & O'Connor, J. (2002). Processing of ultra-high molecular weight polyethylene : modelling the decay of fusion defects. Chemical Engineering Research and Design, 80(A5), 423-431. https://doi.org/10.1205/026387602320224003

A problem in applications of ultra-high molecular weight polyethylene (UHMWPE) is the tendency for components to contain fusion defects, arising during processing of the as-polymerized powder. These defects have been implicated previously in failures... Read More about Processing of ultra-high molecular weight polyethylene : modelling the decay of fusion defects.