Outputs (171)

Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex (2015)
Journal Article
Lindh, J., Okal, M., Herrera-Varela, M., Borg-Karlson, A., Torto, B., Lindsay, S., & Fillinger, U. (2015). Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex. Malaria Journal, 14(3), Article 119. https://doi.org/10.1186/s12936-015-0636-0

Background New strategies are needed to manage malaria vector populations that resist insecticides and bite outdoors. This study describes a breakthrough in developing ‘attract and kill’ strategies targeting gravid females by identifying and evaluati... Read More about Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex.

The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial (2015)
Journal Article
Tiono, A., Pinder, M., N'Fale, S., Faragher, B., Smith, T., Silkey, M., …Lindsay, S. (2015). The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial. Trials, 16, Article 113. https://doi.org/10.1186/s13063-015-0606-4

Background: Recent reductions in malaria in sub-Saharan Africa have been associated with increased coverage with long-lasting insecticidal nets (LLINs). Pyrethroids are currently the only insecticide class used for treating nets, and the rapid increa... Read More about The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial.

Adult vector control, mosquito ecology and malaria transmission (2015)
Journal Article
Brady, O., Godfray, H., Tatem, A., Gething, P., Cohen, J., McKenzie, F., …Smith, D. (2015). Adult vector control, mosquito ecology and malaria transmission. International Health, 7(2), 121-129. https://doi.org/10.1093/inthealth/ihv010

Background: Standard advice regarding vector control is to prefer interventions that reduce the lifespan of adult mosquitoes. The basis for this advice is a decades-old sensitivity analysis of ‘vectorial capacity’, a concept relevant for most malaria... Read More about Adult vector control, mosquito ecology and malaria transmission.

Mind the gap: house structure and the risk of malaria in Uganda (2015)
Journal Article
Wanzirah, H., Tusting, L., Arinaitwe, E., Katureebe, A., Maxwell, K., Rek, J., …Lindsay, S. (2015). Mind the gap: house structure and the risk of malaria in Uganda. PLoS ONE, 10(1), https://doi.org/10.1371/journal.pone.0117396

Background: Good house construction may reduce the risk of malaria by limiting the entry of mosquito vectors. We assessed how house design may affect mosquito house entry and malaria risk in Uganda. Methods: 100 households were enrolled in each of th... Read More about Mind the gap: house structure and the risk of malaria in Uganda.

How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector? (2014)
Journal Article
Stone, C., Lindsay, S., & Chitnis, N. (2014). How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?. PLoS Neglected Tropical Diseases, 8(12), Article e3393. https://doi.org/10.1371/journal.pntd.0003393

Background: The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF) control where both diseases are transmitted by the same vector. To date most examples... Read More about How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?.

Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial (2014)
Journal Article
Pinder, M., Jawara, M., Jarju, L., Salami, K., Jeffries, D., Adiamoh, M., …Lindsay, S. (2015). Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial. The Lancet, 385(9976), 1436-1446. https://doi.org/10.1016/s0140-6736%2814%2961007-2

Background: Although many malaria control programmes in sub-Saharan Africa use indoor residual spraying with long-lasting insecticidal nets (LLINs), the two studies assessing the benefit of the combination of these two interventions gave conflicting... Read More about Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial.

Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis (2014)
Journal Article
Wilson, A., Chen-Hussey, V., Logan, J., & Lindsay, S. (2014). Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis. Malaria Journal, 13(1), Article 446. https://doi.org/10.1186/1475-2875-13-446

Background: Recommended vector control tools against malaria, such as long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), mainly target mosquitoes that rest and feed on human hosts indoors. However, in some malaria-endemic area... Read More about Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis.

The global distribution and transmission limits of lymphatic filariasis: past and present (2014)
Journal Article
Cano, J., Rebollo, M., Golding, N., Pullan, R., Crellen, T., Soler, A., …Brooker, S. (2014). The global distribution and transmission limits of lymphatic filariasis: past and present. Parasites and Vectors, 7(1), https://doi.org/10.1186/s13071-014-0466-x

Background: Lymphatic filariasis (LF) is one of the neglected tropical diseases targeted for global elimination by 2020 and to guide elimination efforts countries have, in recent years, conducted extensive mapping surveys. Documenting the past and pr... Read More about The global distribution and transmission limits of lymphatic filariasis: past and present.

Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis (2014)
Journal Article
Wilson, A., Dhiman, R., Kitron, U., Scott, T., van den Berg, H., & Lindsay, S. (2014). Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis. PLoS Neglected Tropical Diseases, 8(10), Article e3228. https://doi.org/10.1371/journal.pntd.0003228

Introduction: Insecticide-treated nets (ITNs) are one of the main interventions used for malaria control. However, these nets may also be effective against other vector borne diseases (VBDs). We conducted a systematic review and meta-analysis to esti... Read More about Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis.

Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect (2014)
Journal Article
Mbare, O., Lindsay, S., & Fillinger, U. (2014). Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect. Parasites and Vectors, 7, Article 438. https://doi.org/10.1186/1756-3305-7-438

Background: Persistent monomolecular surface films could benefit larval source management for malaria control by reducing programme costs and managing insecticide resistance. This study evaluated the efficacy of the silicone-based surface film, Aquat... Read More about Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect.

Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus (2014)
Journal Article
Mbare, O., Lindsay, S., & Fillinger, U. (2014). Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus. Parasites and Vectors, 7(6), Article 280. https://doi.org/10.1186/1756-3305-7-280

Background: The use of gravid mosquitoes as vehicles to auto-disseminate larvicides was recently demonstrated for the transfer of pyriproxyfen (PPF) by container-breeding Aedes mosquitoes and presents an appealing idea to explore for other disease ve... Read More about Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus.

Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s (2014)
Journal Article
Dugassa, S., Lindh, J., Torr, S., Lindsay, S., & Fillinger, U. (2014). Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s. Parasites and Vectors, 7(6), Article 272. https://doi.org/10.1186/1756-3305-7-272

Background: Electric nets (e-nets) are used to analyse the flight behaviour of insects and have been used extensively to study the host-oriented flight of tsetse flies. Recently we adapted this tool to analyse the oviposition behaviour of gravid mala... Read More about Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s.

A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens (2014)
Journal Article
Guerra, C., Reiner Jr, R., Perkins, T., Lindsay, S., Midega, J., Brady, O., …Smith, D. (2014). A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens. Parasites and Vectors, 7(6), Article 276. https://doi.org/10.1186/1756-3305-7-276

Background: Pathogen transmission by mosquitos is known to be highly sensitive to mosquito bionomic parameters. Mosquito mark-release-recapture (MMRR) experiments are a standard method for estimating such parameters including dispersal, population si... Read More about A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens.

Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system (2014)
Journal Article
Herrera-Varela, M., Lindh, J., Lindsay, S., & Fillinger, U. (2014). Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system. Malaria Journal, 13, Article 133. https://doi.org/10.1186/1475-2875-13-133

Background: The non-random distribution of anopheline larvae in natural habitats suggests that gravid females discriminate between habitats of different quality. Whilst physical and chemical cues used by Culex and Aedes vector mosquitoes for selectin... Read More about Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system.

Framework for rapid assessment and adoption of new vector control tools (2014)
Journal Article
Vontas, J., Moore, S., Kleinschmidt, I., Ranson, H., Lindsay, S., Lengeler, C., …Hemingway, J. (2014). Framework for rapid assessment and adoption of new vector control tools. Trends in Parasitology, 30(4), 191-204. https://doi.org/10.1016/j.pt.2014.02.005

Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) u... Read More about Framework for rapid assessment and adoption of new vector control tools.

Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda (2014)
Journal Article
Kilama, M., Smith, D., Hutchinson, R., Kigozi, R., Yeka, A., Lavoy, G., …Lindsay, S. (2014). Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda. Malaria Journal, 13, Article 111. https://doi.org/10.1186/1475-2875-13-111

Background: The Plasmodium falciparum entomological inoculation rate (PfEIR) is a measure of exposure to infectious mosquitoes. It is usually interpreted as the number of P. falciparum infective bites received by an individual during a season or annu... Read More about Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda.

Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto (2013)
Journal Article
Okal, M., Francis, B., Herrera-Varela, M., Fillinger, U., & Lindsay, S. (2013). Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto. Malaria Journal, 12(10), Article 365. https://doi.org/10.1186/1475-2875-12-365

Background: To date no semiochemicals affecting the pre-oviposition behaviour of the malaria vector Anopheles gambiae sensu lato have been described. Water vapour must be the major chemical signal emanating from a potential larval habitat, and althou... Read More about Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto.

Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis (2013)
Journal Article
Tusting, L., Willey, B., Lucas, H., Thompson, J., Kafy, H., Smith, R., & Lindsay, S. (2013). Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis. The Lancet, 382(9896), 963-972. https://doi.org/10.1016/s0140-6736%2813%2960851-x

Background Future progress in tackling malaria mortality will probably be hampered by the development of resistance to drugs and insecticides and by the contraction of aid budgets. Historically, control was often achieved without malaria-specific int... Read More about Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis.

Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia (2013)
Journal Article
Tangena, J., Majida, A., D'Alessandro, U., Jarju, L., Jawara, M., Jeffries, D., …Pinder, M. (2013). Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia. PLoS ONE, 8(9), Article e74351. https://doi.org/10.1371/journal.pone.0074351

Background: Malaria vector control is threatened by resistance to pyrethroids, the only class of insecticides used for treating bed nets. The second major vector control method is indoor residual spraying with pyrethroids or the organochloride DDT. H... Read More about Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia.

Mosquito larval source management for controlling malaria (2013)
Journal Article
Tusting, L., Thwing, J., Sinclair, D., Fillinger, U., Gimnig, J., Bonner, K., …Lindsay, S. (2013). Mosquito larval source management for controlling malaria. Cochrane Database of Systematic Reviews, 2013(8), Article CD008923. https://doi.org/10.1002/14651858.cd008923.pub2

Background Malaria is an important cause of illness and death in people living in many parts of the world, especially sub-Saharan Africa. Long-lasting insecticide treated bed nets (LLINs) and indoor residual spraying (IRS) reduce malaria transmission... Read More about Mosquito larval source management for controlling malaria.