The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors
(2017)
Journal Article
Haffez, H., Chisholm, D., Valentine, R., Pohl, E., Redfern, C., & Whiting, A. (2017). The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors. MedChemComm, 8(3), 578-592. https://doi.org/10.1039/c6md00680a
All-trans-retinoic acid (ATRA) and its synthetic analogues EC23 and EC19 direct cellular differentiation by interacting as ligands for the retinoic acid receptor (RARα, β and γ) family of nuclear receptor proteins. To date, a number of crystal struct... Read More about The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors.