Outputs (4)

Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events (2019)
Journal Article
Lawton, P., Buckley, C., Saunter, C., Wilson, C., Corbett, A., Salter, P., …Girkin, J. (2019). Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events. Biomedical Optics Express, 10(11), 5611-5624. https://doi.org/10.1364/boe.10.005611

Rapid imaging of multiple focal planes without sample movement may be achieved through remote refocusing, where imaging is carried out in a plane conjugate to the sample plane. The technique is ideally suited to studying the endothelial and smooth mu... Read More about Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events.

VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology (2019)
Journal Article
Lawton, P. F., Lee, M. D., Saunter, C. D., Girkin, J. M., McCarron, J. G., & Wilson, C. (2019). VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology. Frontiers in Physiology, 10, Article 99. https://doi.org/10.3389/fphys.2019.00099

Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of th... Read More about VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology.

Towards a high-throughput real-time confocal microfluidic system for monitoring absorbance spectra in mixed-phase chemical reactions (2017)
Journal Article
Lawton, P., & Girkin, J. (2017). Towards a high-throughput real-time confocal microfluidic system for monitoring absorbance spectra in mixed-phase chemical reactions. Microfluidics and Nanofluidics, 21(4), Article 69. https://doi.org/10.1007/s10404-017-1904-9

In this work, we present a compact, real-time absorbance spectroscopy instrument, designed with a particular focus on taking spectroscopic readings in a microfluidic channel environment and selectively analysing an active volume in this channel by ad... Read More about Towards a high-throughput real-time confocal microfluidic system for monitoring absorbance spectra in mixed-phase chemical reactions.

Combining optical trapping in a microfluidic channel with simultaneous micro-Raman spectroscopy and motion detection
Presentation / Conference Contribution
Lawton, P., Saunter, C., & Girkin, J. (2014, March). Combining optical trapping in a microfluidic channel with simultaneous micro-Raman spectroscopy and motion detection. Presented at Microfluidics, BioMEMS, and Medical Microsystems XII, San Francisco, California, United States

Since their invention by Ashkin optical tweezers have demonstrated their ability and versatility as a non-invasive tool for micromanipulation. One of the most useful additions to the basic optical tweezers system is micro-Raman spectroscopy, which pe... Read More about Combining optical trapping in a microfluidic channel with simultaneous micro-Raman spectroscopy and motion detection.