Outputs (4)

Lytic reactions of drugs with lipid membranes (2018)
Journal Article
Britt, H. M., García-Herrero, C. A., Denny, P. W., Mosely, J. A., & Sanderson, J. M. (2019). Lytic reactions of drugs with lipid membranes. Chemical Science, 10(3), 674-680. https://doi.org/10.1039/c8sc04831b

Propranolol is shown to undergo lipidation reactions in three types of lipid membrane: (1) synthetic single-component glycerophospholipid liposomes; (2) liposomes formed from complex lipid mixtures extracted from E. coli or liver cells; and (3) in ce... Read More about Lytic reactions of drugs with lipid membranes.

Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding (2014)
Journal Article
Curtis, F., Malay, A., Trotter, A., Wilson, L., Barradell-Black, M., Bowers, L., …Sharples, G. (2014). Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding. PLoS ONE, 9(8), Article e102454. https://doi.org/10.1371/journal.pone.0102454

Genetic and biochemical evidence suggests that λ Orf is a recombination mediator, promoting nucleation of either bacterial RecA or phage Redβ recombinases onto single-stranded DNA (ssDNA) bound by SSB protein. We have identified a diverse family of O... Read More about Phage Orf family recombinases: conservation of activities and involvement of the central channel in DNA binding.

Influence of Lipids on the Interfacial Disposition of Respiratory Syncytical Virus Matrix Protein (2011)
Journal Article
McPhee, H., Carlisle, J., Beeby, A., Money, V., Watson, M., Yeo, R., & Sanderson, J. (2011). Influence of Lipids on the Interfacial Disposition of Respiratory Syncytical Virus Matrix Protein. Langmuir, 27(1), 304-311. https://doi.org/10.1021/la104041n

The propensity of a matrix protein from an enveloped virus of the Mononegavirales family to associate with lipids representative of the viral envelope has been determined using label-free methods, including tensiometry and Brewster angle microscopy o... Read More about Influence of Lipids on the Interfacial Disposition of Respiratory Syncytical Virus Matrix Protein.

Surface features of a Mononegavirales matrix protein indicate sites of membrane interaction (2009)
Journal Article
Money, V., McPhee, H., Mosely, J., Sanderson, J., & Yeo, R. (2009). Surface features of a Mononegavirales matrix protein indicate sites of membrane interaction. Proceedings of the National Academy of Sciences, 106(11), 4441-4446. https://doi.org/10.1073/pnas.0805740106

The matrix protein (M) of respiratory syncytial virus (RSV), the prototype viral member of the Pneumovirinae (family Paramyxoviridae, order Mononegavirales), has been crystallized and the structure determined to a resolution of 1.6 A. The structure c... Read More about Surface features of a Mononegavirales matrix protein indicate sites of membrane interaction.