Outputs (2)

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle (2016)
Journal Article
Chalmers, S., Saunter, C., Girkin, J., & McCarron, J. (2016). Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle. The Journal of Physiology, 594(15), 4283-4295. https://doi.org/10.1113/jp271942

Mitochondrial function, motility and architecture are each central to cell function. Age-associated mitochondrial dysfunction may contribute to vascular disease. However, mitochondrial changes in ageing remain ill-defined because of the challenges of... Read More about Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle.

Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium (2016)
Journal Article
Wilson, C., Saunter, C. D., Girkin, J. M., & McCarron, J. G. (2016). Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium. FASEB Journal, 30(5), 2000-2013. https://doi.org/10.1096/fj.201500090

Agonist-mediated signaling by the endothelium controls virtually all vascular functions. Because of the large diversity of agonists, each with varying concentrations, background noise often obscures individual cellular signals. How the endothelium di... Read More about Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium.