CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6
(2021)
Journal Article
Maruyama, Y., Sugawa, M., Yamaguchi, S., Davies, T., Osaki, T., Kobayashi, T., Yamagishi, M., Takeuchi, S., Mishima, M., & Yajima, J. (2021). CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6. Communications Biology, 4, Article 180. https://doi.org/10.1038/s42003-021-01704-2
Centralspindlin, a complex of the MKLP1 kinesin-6 and CYK4 GAP subunits, plays key roles in metazoan cytokinesis. CYK4-binding to the long neck region of MKLP1 restricts the configuration of the two MKLP1 motor domains in the centralspindlin. However... Read More about CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6.