CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation
(2015)
Journal Article
Davies, T., Kodera, N., Kaminski Schierle, G. S., Rees, E., Erdelyi, M., Kaminski, C. F., Ando, T., & Mishima, M. (2015). CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation. PLoS Biology, 13(4), Article e1002121. https://doi.org/10.1371/journal.pbio.1002121
Centralspindlin, a constitutive 2:2 heterotetramer of MKLP1 (a kinesin-6) and the non-motor subunit CYK4, plays important roles in cytokinesis. It is crucial for the formation of central spindle microtubule bundle structure. Its accumulation at the c... Read More about CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation.