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Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions (2019)
Journal Article
Brittain, W. D., & Cobb, S. L. (2019). Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions. Organic and Biomolecular Chemistry, 17(8), 2110-2115. https://doi.org/10.1039/c8ob02899k

Phenols are extremely valuable building blocks in the areas of pharmaceuticals, natural products, materials and catalysts. In order to carry out modifications on phenols, the phenolic oxygen is routinely protected to prevent unwanted side reactions.... Read More about Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions.