Professor Ann O'Donoghue's Outputs (2)

The Synthesis, Conformation and Hydrolytic Stability of an N,S-bridging Thiophosphoramidate Analogue of Thymidylyl-3ʹ,5ʹ-Thymidine (2016)
Journal Article
Conway, L., Mikkola, S., O’Donoghue, A., & Hodgson, D. (2016). The Synthesis, Conformation and Hydrolytic Stability of an N,S-bridging Thiophosphoramidate Analogue of Thymidylyl-3ʹ,5ʹ-Thymidine. Organic and Biomolecular Chemistry, 14(30), 7361-7367. https://doi.org/10.1039/c6ob01270a

A 3'-N,5'-S-bridging thiophosphoramidate analogue of thymidylyl-3ʹ,5ʹ-thymidine was synthesised under aqueous conditions. 1H NMR conformational measurements show that the 3'-N-substituted deoxyribose ring is biased towards the 'north', RNA-like confo... Read More about The Synthesis, Conformation and Hydrolytic Stability of an N,S-bridging Thiophosphoramidate Analogue of Thymidylyl-3ʹ,5ʹ-Thymidine.

Proton transfer reactions of a bridged bis-propyl bis-imidazolium salt (2016)
Journal Article
Massey, R. S., Quinn, P., Zhou, S., Murphy, J. A., & O'Donoghue, A. C. (2016). Proton transfer reactions of a bridged bis-propyl bis-imidazolium salt. Journal of Physical Organic Chemistry, 29(12), 735-740. https://doi.org/10.1002/poc.3567

Tetraazafulvalene 1 has found broad application in reduction and other related transformations and is conveniently generated from bis-propyl bis-imidazolium salt 4 with a strong base in a non-protic solvent. The proposed mechanism for the formation o... Read More about Proton transfer reactions of a bridged bis-propyl bis-imidazolium salt.