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Professor Ann O'Donoghue's Outputs (1)

Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase (2001)
Journal Article
Amyes, T., O'Donoghue, A., & Richard, J. (2001). Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase. Journal of the American Chemical Society, 123(45), 11325-11326. https://doi.org/10.1021/ja016754a

We report that 80% of the enzymatic rate acceleration for the prototypical proton transfer from carbon catalyzed by triosephosphate isomerase can be directly attributed to the remote phosphodianion group of the substrate (R)-glyceraldehyde 3-phosphat... Read More about Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase.