Dr Gary Sharples' Outputs (83)

A novel repeated DNA sequence located in the intergenic regions of bacterial chromosomes. (1990)
Journal Article
Sharples, G., & Lloyd, R. (1990). A novel repeated DNA sequence located in the intergenic regions of bacterial chromosomes. Nucleic Acids Research, 18(22), 6503-6508

We report the discovery of a novel group of highly conserved DNA sequences located within the intergenic regions of the chromosomes of Escherichia coli, Salmonella typhimurium and other bacteria. These intergenic repeat units (IRUs) are 124-127 nucle... Read More about A novel repeated DNA sequence located in the intergenic regions of bacterial chromosomes..

Molecular and functional analysis of the ruv region of Escherichia coli K-12 reveals three genes involved in DNA repair and recombination. (1990)
Journal Article
Sharples, G., Benson, F., Illing, G., & Lloyd, R. (1990). Molecular and functional analysis of the ruv region of Escherichia coli K-12 reveals three genes involved in DNA repair and recombination. Molecular Genetics and Genomics, 221(2), 219-226

Recombinant plasmids carrying ruvA, ruvB, or both were constructed and used to investigate the genetic defects in a collection of UV-sensitive ruv mutants. The results revealed that efficient survival of UV-irradiated cells depends on both ruvA and r... Read More about Molecular and functional analysis of the ruv region of Escherichia coli K-12 reveals three genes involved in DNA repair and recombination..

Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes. (1988)
Journal Article
Benson, F., Illing, G., Sharples, G., & Lloyd, R. (1988). Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes. Nucleic Acids Research, 16(4), 1541-1549

The nucleotide sequence of a 2505 bp region of the Escherichia coli chromosome containing the LexA regulated ruv gene has been determined. A sequence of 1631 bp encoding two non-overlapping open reading frames that constitute a single operon and whic... Read More about Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes..