Professor Adam Benham's Outputs (2)

A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells (2007)
Journal Article
van Lith, M., Karala, A., Bown, D., Gatehouse, J., Ruddock, L., Saunders, P., & Benham, A. (2007). A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells. Molecular Biology of the Cell, 18(8), 2795-2804. https://doi.org/10.1091/mbc.e07-02-0147

Glycoprotein folding is mediated by lectin-like chaperones and protein disulfide isomerases (PDIs) in the endoplasmic reticulum (ER). Calnexin and the PDI homologue ERp57 work together to help fold nascent polypeptides with glycans located toward the... Read More about A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells.

Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes (2007)
Journal Article
Lemin, A., Saleki, K., van Lith, M., & Benham, A. (2007). Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes. FEBS Letters, 581(9), 1819-1824. https://doi.org/10.1016/j.febslet.2007.03.069

Misfolding of major histocompatibility complex (MHC) class I molecules has been implicated in the rheumatic autoimmune disease ankylosing spondylitis (AS), and has been linked to the unfolded protein response (UPR) in rodent AS models. XBP1 and ATF6α... Read More about Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes.